Neutrophils are a main source of circulating suPAR predicting outcome in critical illness

ConclusionsThe inverse correlation between low uPAR surface expression on neutrophils and high serum suPAR in critically ill patients supports that neutrophils are a main source of shed suPAR proteins in systemic inflammation. Furthermore, high suPAR levels and low neutrophilic uPAR expression predict mortality in ICU patients.

Source: Journal of Intensive Care - April 26, 2019 Category: Intensive Care Source Type: research