Mebendazole-induced M1 polarisation of THP-1 macrophages may involve DYRK1B inhibition

We recently showed that the anti-helminthic compound mebendazole (MBZ) has immunomodulating activity by inducing a M2 to M1 phenotype switch in monocyte/macrophage models. In the present study we investigated ...

Source: BMC Research Notes - April 22, 2019 Category: Research Authors: Kristin Blom, Jenny Rubin, Malin Berglund, Malin Jarvius, Lena Lenhammar, Vendela Parrow, Claes Andersson, Angelica Loskog, M årten Fryknäs, Peter Nygren and Rolf Larsson Tags: Research note Source Type: research