251 Natural history of wounds in patients with recessive dystrophic epidermolysis bullosa

Recessive dystrophic epidermolysis bullosa (RDEB) patients suffer from recalcitrant, painful blistering and open wounds, however, a systematic natural history of RDEB wounds with patient reported outcomes such as pain and itch has not been conducted. We hypothesized that RDEB patients have 2 major types of wounds, chronic wounds, defined as those that stay open for ≥ 12 weeks, and recurrent wounds, which heal but reblister easily, and that these wounds differ in size, pain, and itch. Recruited from Stanford's EB clinic, 40 patients completed a questionnaire to evaluate the size, duration, and associated symptoms of chronic and recurrent wounds.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Epidemiology Source Type: research