Hyperglycemia affects global 5-methylcytosine and 5-hydroxymethylcytosine in blood genomic DNA through upregulation of SIRT6 and TETs

Accumulating evidence suggests that epigenetic changes play key roles in the pathogenesis of type 2 diabetes mellitus (T2DM). However, the dynamic regulation of 5-methylcytosine (5mC) and 5-hydroxymethylcytosi...

Source: Clinical Epigenetics - April 15, 2019 Category: Research Authors: Er-Feng Yuan, Ying Yang, Lin Cheng, Xujing Deng, Shao-Min Chen, Xin Zhou and Song-Mei Liu Tags: Research Source Type: research