Successful peritoneal dialysis for the end-stage kidney disease associated with Prader –Willi syndrome: a case report

In this report, we experienced o ne case of patient with PWS suffering from ESKD due to DKD who started PD as an initial RRT and succeeded to continue for total of 40 months. The patient was 37-year-old man at the time of initiation of dialysis. PD was chosen for RRT because we suspected that he might have more technical difficult ies for continuing HD. After several episodes of peritonitis, he successfully continues PD without peritonitis for next 27 months until the present time with good support by his family member. To our best knowledge, this is the first reported case of ESKD associated with PWS who was successfully tr eated with PD for long period.
Source: CEN Case Reports - Category: Urology & Nephrology Source Type: research

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Publication date: Available online 21 September 2019Source: PeptidesAuthor(s): Camilla F. Thomsen, Mathias Ried-Larsen, Jens P. Goetze, Lars B. Andersen, Jens Faber, Anders Grøntved, Jørgen L. JeppesenAbstractAtrial natriuretic peptide (ANP) is known for its natriuretic, diuretic, and vasodilatory properties. However, ANP also has metabolic effects stimulating lipolysis and lipid oxidation. Overweight individuals have decreased circulating ANP concentrations. It has been proposed that this potential ANP deficiency could have biological consequences in overweight-related disorders, including decreased lipolysi...
Source: Peptides - Category: Biochemistry Source Type: research
Publication date: Available online 20 September 2019Source: Advances in Space ResearchAuthor(s): Madeeha Talha, Nabeel Ahmed, Muneeza M. Ali, Ghulam MurtazaAbstractThe variability of NmF2 during solar minima of solar cycle 21-22, 22-23 and 23-24 has been studied for two low latitude stations, Karachi (Pakistan) and Okinawa (Japan), as both stations are situated at the Equatorial Ionization Anomaly (EIA) crest region. Diurnal, seasonal and annual behaviour of variability has been investigated using relative standard deviation approach. At both the stations, a direct relation of variability (CV) with Smoothed Sunspot Numbers...
Source: Advances in Space Research - Category: Science Source Type: research
The objective of this study was to compare the practices of surgeons in France versus other countries regarding the diagnosis and treatment of IIS.HypothesisDiagnostic and therapeutic practices regarding IIS differ between surgeons in France and in other countries.Material and methodsA 21-item questionnaire in French and English was emailed to the 1300 members of the French Arthroscopy Society and to surgeons from countries other than France. The questionnaire collected information on knowledge about IIS (2 items), the frequency of IIS in clinical practice (2 items), the diagnosis of IIS (6 items), the non-operative and su...
Source: Orthopaedics and Traumatology: Surgery and Research - Category: Orthopaedics Source Type: research
It's no secret that there's a multitude of unhappy nurses out there in the world. From mandatory overtime to unhealthy nurse-patient ratios, I admit there are very valid reasons for this seeming epidemic of discontent. So, is the nursing glass half-full or half-empty? I guess it depends on who you're drinking with (and perhaps what you're drinking). Photo by Jana Sabeth on UnsplashReasons To Be Cheerful---Or NotThis blog post isn't really about the aforementioned multitude of reasons that explain nurses'rampant unhappiness. A new study mentioned recently on Twitter states that a full one-third of nurses...
Source: Digital Doorway - Category: Nursing Tags: nurse nurse identity nurses nursing nursing careers nursing identity Source Type: blogs
CONCLUSIONS: Our study firstly established that the G allele and C/G genotype of rs184187143 single nucleotide polymorphism (SNP) in SLC26A6 gene was closely linked with the increased risk for the development of the diabetic ketoacidosis of GDM. PMID: 31539142 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
CONCLUSIONS: TUG1 is downregulated in DN. The overexpression of TUG1 could suppress the proliferation and ECM accumulation of mesangial cells via inhibiting the PI3K/AKT pathway. PMID: 31539141 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
We report a case of septic shock caused by this pathogen. A 78-year-old man affected by diabetes and hypertension was admitted for fever in our Emergency Department. He reported fever (37.7°C) with normal values of blood pressure, heart rate and saturation of oxygen. Laboratory studies showed increased values of procalcitonin and normal white-cell level. Blood cultures were collected and an empirical antibiotic therapy was started. He reported six days earlier a bite of a dog at the right hand. During the following days the patient presented a deterioration of clinical conditions with fever, asthenia and comparison of ...
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Spontaneous Model of Sjögren's Syndrome in NOD Mice. Curr Protoc Pharmacol. 2019 Sep;86(1):e65 Authors: Scuron MD, Fay B, Oliver J, Smith P Abstract The non-obese diabetic (NOD) mouse model is the most widely described and validated method for investigating human primary Sjögren's syndrome (SS) and represents a useful model for translational studies. However, the systemic disease manifestation in NOD mice is sensitive to the housing environment, as stress modulates the immune system, so it is essential to confirm that readouts are robust, reproducible, and sensitive to known clinical treatmen...
Source: Current Protocols in Pharmacology - Category: Drugs & Pharmacology Tags: Curr Protoc Pharmacol Source Type: research
The objective of this study was to compare the preoperative serum levels of DPP-4 in patients with and without surgical finding of perivesicular inflammation. Materials and methods: a cross-sectional analytical study nested in a prospective cohort, including patients scheduled for elective cholecystectomy, without surgical complications, that were 18-70 years of age, with low cardiovascular risk, without a history of peritonitis, pancreatitis, or jaundice and underwent ERCP protocol, type 2 diabetes mellitus, acute inflammatory (Protein C Reactive
Source: Medicina (Kaunas) - Category: Universities & Medical Training Authors: Tags: Medicina (Kaunas) Source Type: research
Publication date: Available online 21 December 2018Source: Journal of Advanced ResearchAuthor(s): Undurti N. DasAbstractIt has been suggested that hepatitis B virus (HBV)- and hepatitis C virus (HCV)-induced hepatic damage and cirrhosis and associated hypoalbuminemia, non-alcoholic fatty liver disease (NAFLD), and alcoholic fatty liver disease (AFLD) are due to an imbalance between pro-inflammatory and anti-inflammatory bioactive lipids. Increased tumour necrosis factor (TNF)-α production induced by HBV and HCV leads to a polyunsaturated fatty acid (PUFA) deficiency and hypoalbuminemia. Albumin mobilizes PUFAs from t...
Source: Journal of Advanced Research - Category: Research Source Type: research
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