Secondary metabolites from the Chinese liverwort Diplophyllum apiculatum

Publication date: June 2019Source: Phytochemistry Letters, Volume 31Author(s): Shenghua Fan, Yi Li, Jinchuan Zhou, Yanan Qiao, Chunyang Zhang, Yun Gao, Xueyang Jin, Jiaozhen Zhang, Wang Chen, Hongxiang LouAbstractThree new clerodane-type diterpenoids, diplapiculins A–C (1-3), together with five known compounds (4-8) were isolated from the Chinese liverwort Diplophyllum apiculatum (A. Evans) Stephani. Their structures were determined by detailed analysis of HRMS and NMR data, coupled with single-crystal X-ray diffraction crystallography and electronic circular dichroism (ECD). They were found no antifungal and anticancer effects in preliminary biotests in vitro.Graphical abstract

Source: Phytochemistry Letters - March 31, 2019 Category: Chemistry Source Type: research