Effect of oral phytoestrogens on endometrial thickness and breast density of perimenopausal and postmenopausal women: a systematic review and meta-analysis

Given the increase in life expectancy, women have to spend 30 years approximately at postmenopausal status [1]. The lack of estrogens leads, among other consequences, to vasomotor (mainly hot flashes and night sweats) and vulvovaginal symptoms (mainly vaginal atrophy and dyspareunia), affecting woman's daily routine and having a negative impact on her quality of life [2]. Menopausal Hormone Therapy (MHT) is the treatment of choice for vasomotor and vulvovaginal symptoms [3]. However, some women cannot receive MHT, because of relative or absolute contraindications or the fear for possible adverse effects on endometrium and breast.
Source: Maturitas - Category: Primary Care Authors: Source Type: research