Downregulation of T-Cell Transcription Factors in Adult Latent Autoimmune Diabetes with High-Titer Glutamic Acid Decaroxylase Antibody

ConclusionLADA patients with high-titer GADA express lower levels of T-cell transcription factors, including the Treg transcription factor FOXP3, which may contribute to differences in the clinical profile compared to LADA patients with low-titer GADA.Trial RegistrationClinicalTrials.gov identifier, NCT01159847.
Source: Diabetes Therapy - Category: Endocrinology Source Type: research