Factors that Impact Fertility after Hysteroscopic Adhesiolysis for Intrauterine Adhesions and Amenorrhea: A Retrospective Cohort Study

ConclusionYounger age, earlier treatment within disease course, fewer cervical canal adhesions, and fewer surgical procedures improve reproductive outcome in patients with severe IUAs and amenorrhea.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research

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ConclusionThis pioneer study involving Brazilian women showed no association among the studied polymorphisms and PE, which suggests that ins/del ACE and SNPs ESR1 do not contribute to this disease occurrence in Brazil.
Source: Molecular and Cellular Probes - Category: Molecular Biology Source Type: research
This article reviews the treatment of herpes simplex virus, cytomegalovirus, hepatitis B and C viruses, and human immunodeficiency virus during pregnancy. PMID: 31010558 [PubMed - in process]
Source: Herpes - Category: Infectious Diseases Authors: Tags: Clin Perinatol Source Type: research
Publication date: Available online 24 April 2019Source: Reproductive ToxicologyAuthor(s): Annia A. Martínez-Peña, Andrea Peña-Castillo, L. Yuliana Parra-Forero, Isabel Hernández-Ochoa, Luis R. Hernández-Barrientos, Sumiko Morimoto, C. Adriana Mendoza RodríguezAbstractThe aim was to evaluate the effect of perinatal BPA exposure of one or both parents on the implantation index and expression of talin, occludin and E-cadherin in the uterine epithelial cells (UEC) of the offspring. Pregnant Wistar dams (F0) received BPA or vehicle from gestational day (GD) 6 to lactation day 21. F1 ani...
Source: Reproductive Toxicology - Category: Toxicology Source Type: research
The objective of this CFAS guideline is to provide evidence-based recommendations using the GRADE (Grading of Recommendations, Assessment, Development and Evaluations) framework on the assessment, impact and management of thin endometrium in assisted reproduction. The effect of endometrial thickness on pregnancy and live birth outcomes in ovarian stimulation and IVF (fresh and frozen cycles) is addressed. In addition, recommendations on the use of adjuvants to improve endometrial thickness and pregnancy outcomes are provided.
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
Conclusion(s)Discordant twin pregnancies were at increased risk for one fetal loss prior to 12 weeks’ gestation. Except for birth weight discordance, there was no significant difference between CRL discordance and other adverse perinatal outcomes.
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
Publication date: Available online 25 April 2019Source: Reproductive BioMedicine OnlineAuthor(s): Lise Preaubert, Talya Shaulov, Simon Phillips, Melissa Stutz, Isaac Jacques Kadoch, Camille Sylvestre, Pierre LehmannAbstractResearch questionDo live birth rates (LBR) following modified natural IVF (mnIVF) differ according to serum AMH level?DesignRetrospective cohort study including 638 women aged ≤ 39 years starting their first mnIVF cycle at a university-affiliated private IVF center. Patients were divided into three groups, by level of AMH: ≤ 0.5 ng/ml (25th percentile), 0.51-2.03 ng/ml (25-75th, reference), and 2.0...
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
Publication date: Available online 25 April 2019Source: Reproductive BioMedicine OnlineAuthor(s): Angelos Youssef, Nathalie Vermeulen, E. E. Lisa O. Lashley, Mariëtte Goddijn, Marie Louise P. van der HoornAbstractDiagnostic investigations and treatment options of recurrent pregnancy loss (RPL) may differ locally and internationally. This manuscript reviews the similarities and differences between existing (inter)national guidelines on RPL. The European Society of Human Reproduction and Embryology (ESHRE) guideline (2017), the American Society for Reproductive Medicine (ASRM) Committee Opinions (2013) and the Royal Col...
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
Male infertility is a heterogenous disease process requiring the proper functioning and interaction of thousands of genes. Given the number of genes involved, it is thought that genetic causes contribute to most cases of infertility. Identifying these causes, however, is challenging. Infertility is associated with negative health outcomes, such as cancer, highlighting the need to further understand the genetic underpinnings of this condition. This paper describes the genetic and genomic tests currently available to identify the etiology of male infertility and then will discuss emerging technologies that may facilitate dia...
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Views and reviews Source Type: research
This paper discusses the variety of effective sperm selection techniques that have been developed for use in assisted reproductive technologies. Available methods for isolating the competent sperm in an ejaculate are outlined, as well as techniques for selecting single sperm for use in intracytoplasmic sperm injection procedures. Case-specific methods for selecting the most competent sperm are discussed, with reference to the potential causes of male factor infertility and guidance for the embryologist based on the issues present for each couple seeking treatment.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Views and reviews Source Type: research
Infertility due to obstructive azoospermia may be treated effectively by surgical reconstruction or by retrieval of sperm from the epididymis or testis, followed by in  vitro fertilization with intracytoplasmic sperm injection. This replaces the ASRM documents titled “Sperm retrieval for obstructive azoospermia” and “The management of infertility due to obstructive azoospermia,” last published in 2008.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: ASRM pages Source Type: research
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