Rites of Passage: Call Me Cozy

As I struggle with chronic pain, cozy for me is less hygge and more my ex-boyfriend ’ s mother, nurses with juice and weird, sandy doughnuts.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Books and Literature Lyme Disease Dunham, Lena your-feed-selfcare Ehlers-Danlos Syndrome Endometriosis Source Type: news

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The objectives of this article are the following: 1) to examine fibromyalgia and somatic symptom disorder analogy. 2) to discuss stress-evoked neuropathic pain sexual dimorphism, and 3) to propose a neuropathic pathogenesis that may explain how stressed women could develop fibromyalgia. Recent research demonstrates a clear link between fibromyalgia and small fibre neuropathy. Dorsal root ganglia contain the small nerve fibre nuclei. In rodents, physical, chemical, or environmental stressors lead to dorsal root ganglia phenotypic changes and to hyperalgesia. This phenomenon is much more frequent in females. Prolactin, oestr...
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
Authors: van Campen C(MC, Rowe PC, Verheugt FWA, Visser FC Abstract OBJECTIVES: Muscle pain and fibromyalgia (FM) are common among individuals with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). We recently demonstrated that during orthostatic stress testing, adults with ME/CFS reported increased pain. In the current study, we hypothesised that pain pressure thresholds (PPT) would decrease and temporal summation (windup) would increase after head-up tilt testing (HUT), and that the presence of co-morbid FM would be associated with greater change in both measures. METHODS: We studied adult ME/CFS p...
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
Discussion: The use of biologic agents did not increase in this interval, but it is higher than in an earlier assessment of the NAMCS. Nearly all systemic immunomodulators are prescribed by dermatologists. The ambulatory uptake of these agents did not alter the use of other treatment modalities within this timeframe. PMID: 32940551 [PubMed - as supplied by publisher]
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research
Conclusions: The use of the standardized MIST tool for EMS to hospital patient handoff was associated with a mixed value on inpatient documentation of prehospital events. After MIST implementation, agreement was higher for mechanism and location of injury and lower for vital signs and treatments. Further research can advance the prehospital to treatment facility handoff process. PMID: 32940577 [PubMed - as supplied by publisher]
Source: Prehospital Emergency Care - Category: Endocrinology Tags: Prehosp Emerg Care Source Type: research
Authors: Fernández-Carvajal A, González-Muñiz R, Fernández-Ballester G, Ferrer-Montiel A Abstract INTRODUCTION: . Thermo transient receptor potential (thermoTRP) channels are some of the most intensely pursued therapeutic targets of the past decade. They are considered promising targets of numerous diseases including chronic pain and cancer. Modulators of these proteins, in particular TRPV1-4, TRPM8 and TRPA1, have reached clinical development, but none have been approved for clinical practice yet. AREAS COVERED: . The therapeutic potential of targeting thermoTRP channels is discusse...
Source: Expert Opinion on Investigational Drugs - Category: Drugs & Pharmacology Tags: Expert Opin Investig Drugs Source Type: research
Publication date: November 2020Source: Multiple Sclerosis and Related Disorders, Volume 46Author(s): Mia T. Minen, Kathryn B. Schaubhut, Kaitlyn Morio
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
Authors: Theodosis-Nobelos P, Filotheidou A, Triantis C Abstract The clinical role of the placebo effect is a topic of increasing interest for the scientific community. Focus is shifting from the inert role of placebos in randomized controlled trials (RCTs) to potential effects in clinical applications, since the phenomenon is thought to be inherent in routine clinical practice, affecting therapy success rates. Mediation of the mind-brain-body relationship involves both psychosocial and neurobiological factors, the interaction of which comprises the placebo mechanisms. Psychosocial factors include environmentally i...
Source: Hormones - Category: Endocrinology Tags: Hormones (Athens) Source Type: research
Fibrous dysplasia/McCune-Albright syndrome (FD/MAS) is a mosaic disease resulting in fractures, pain, and disability. G α s mutations disrupt differentiation of skeletal stem cells, leading to marrow fibrosis and increased bone-resorbing osteoclasts. The resulting bone develops one or many expansile, deforming lesions. There are no effective treatments for FD/MAS, and clinical studies have been challenging due to knowledge gaps in pathogenesis, natural history, and clinically relevant endpoints for clinical trials. Anti-resorptive therapy with bisphosphonates has been advocated due to prominent osteoclastogenesis in ...
Source: Videocast - All Events - Category: General Medicine Tags: Upcoming Events Source Type: video
ARTHRITIS pain affects about 10 million people in the UK, and can lead to joint pain and inflammation. You could be at risk of developing arthritis symptoms if you develop a flaky scalp on your head. Should you speak to a doctor about arthritis signs?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Conclusions: The main effects of T. s. stejnegeri envenomation are tissue swelling, pain, and local ecchymosis. We do not recommend the use of cold packs during first aid to reduce wound pain, as this may be a risk factor for wound necrosis. In addition, patients with bulla or blister formation should be carefully examined for subsequent wound necrosis. Antiplatelet use may worsen systemic bleeding. No severe rhabdomyolysis or renal failure was observed in this large case series, we therefore considered that they were not prominent effects of T. s. stejnegeri bite.
Source: Journal of Venomous Animals and Toxins including Tropical Diseases - Category: Tropical Medicine Source Type: research
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