Antibiotic management of urinary tract infection in elderly patients in primary care and its association with bloodstream infections and all cause mortality: population based cohort study

This journal article concludes that in elderly patients with a diagnosis of UTI in primary care, no antibiotics and deferred antibiotics were associated with a significant increase in bloodstream infection and all cause mortality compared with immediate antibiotics. In the context of an increase of Escherichia coli bloodstream infections in England, early initiation of recommended first line antibiotics for UTI in the older population is advocated.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news

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, quite literally! In the inaugural volume of the Journal of Urology published in 1917, Shohl and Janney demonstrated that urine pH 4.6 to 5.0 was lethal for several strains of Escherichia coli.1 Even to this day, therapeutic acidification of the urine is often recommended for suppression of urinary tract infections (UTI).
Source: Kidney International - Category: Urology & Nephrology Authors: Tags: Nephrology Digest Source Type: research
Hundreds of readers shared their experiences with drug-resistant U.T.I.s, many describing deep frustration with persistent, painful infections.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Drug Resistance (Microbial) Urinary Tract E Coli (Bacteria) Infections your-feed-healthcare Source Type: news
In this study we inoculated ground chicken meat with 25 individual isolates of clinical uropathogenic E. coli (UPEC) and newborn meningitis causing E. coli (NMEC), isolates from retail chicken meat (CM), as well as retail chicken-skin isolates identified in our laboratory (CS). We then determined their gamma radiation inactivation kinetics (D10-value). The mean D10-value for all isolates (n = 25) was 0.30 kGy. The mean D10-value for the UPEC, NMEC, CM, and CS isolates were 0.25, 0.29, 0.29, and 0.39 kGy, respectively. The mean D10-value for the clinical isolates was 0.27 kGy vs. 0.34 kGy for the non-clinical is...
Source: Food Microbiology - Category: Food Science Authors: Tags: Food Microbiol Source Type: research
Hundreds of readers shared their experiences with drug-resistant U.T.I.s, many describing deep frustration with persistent, painful infections.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Drug Resistance (Microbial) Urinary Tract E Coli (Bacteria) Infections your-feed-healthcare Source Type: news
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Source: Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
ConclusionExtended-spectrum beta-lactamase-producingE. coli should be suspected in community-acquired upper urinary tract infections. Therefore, when treating patients, it is necessary to focus on antibiotic susceptibility and the prevalence of extended-spectrum beta-lactamase-producing bacteria found in each area. Flomoxef and cefmetazole are useful primary treatments for upper urinary tract infections caused by extended-spectrum beta-lactamase-producingE. coli.
Source: Clinical and Experimental Nephrology - Category: Urology & Nephrology Source Type: research
AbstractRecent studies show that rectal colonization with low-level ciprofloxacin-resistantEscherichia coli (ciprofloxacin minimal inhibitory concentration (MIC) above the epidemiological cutoff point, but below the clinical breakpoint for resistance), i.e., in the range>  0.06–0.5 mg/L is an independent risk factor for febrile urinary tract infection after transrectal ultrasound-guided biopsy (TRUS-B) of the prostate, adding to the other risk posed by established ciprofloxacin resistance inE. coli (MIC  >  0.5 mg/L) as currently defined. We aimed to identify the quinolone that by...
Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research
Conclusion: The present study has shown the production of various virulent factors and developing drug resistance in UPEC. Treatment outcomes of patients harboring strains with no virulence factors seem to be better than the ones which contain multiple virulence factors. UPEC occurs because of multiple virulence factors. Biofilm formation and MRHA are more likely to be seen in catheterized patients. The drug resistance among UPEC is on rise; therefore, the selection of appropriate antibiotics (after antibiotic susceptibility testing) is must for proper treatment of patients and to avoid emergence of drug resistance. Signif...
Source: Annals of African Medicine - Category: African Health Authors: Source Type: research
Abstract The purpose of this research is to compare and enhance the antimicrobial and antibiofilm potentials of the biogenic selenium nanoparticles (Se NPs) produced by cost-effective and eco-friendly green methods. The synthesis of Se NPs is described in this manuscript by two different methods: a biogenic process using Penicillium chrysogenum filtrate and by utilizing gentamicin drug (CN) following the application of gamma irradiation. Se NPs were characterized by UV-Vis., HRTM, FTIR, XRD, DLS, SEM, and EDX mapping technique. Antimicrobial and antibiofilm activities of the synthesized Se NPs were investigated ag...
Source: Biological Trace Element Research - Category: Biology Authors: Tags: Biol Trace Elem Res Source Type: research
Microbial Drug Resistance, Ahead of Print.
Source: Microbial Drug Resistance - Category: Microbiology Authors: Source Type: research
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