GSE124757 Phosphatase inhibitor PPP1R11 modulates resistance of human T cells towards Treg-mediated suppression of TCR signaling

Contributors : Sunjay J Fernandes ; Rubin N Joshi ; Angelika SchmidtSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensWe have performed RNAseq analysis of human T cells upon PPP1R11 siRNA silencing. We have explored the role of PPP1R11 for the first time in primary human T cells and discovered that PPP1R11 is a novel negative mediator of T cell activation.

Source: GEO: Gene Expression Omnibus - March 8, 2019 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research