Diagnostic Accuracy of Ocular Vestibular Evoked Myogenic Potentials for Superior Canal Dehiscence Syndrome in a Large Cohort of Dizzy Patients

Objectives:
To determine the diagnostic accuracy of ocular vestibular evoked myogenic potentials (oVEMPs) for superior canal dehiscence syndrome (SCDS) in a large cohort of unselected dizzy patients. Most SCDS patients are dizzy (90%); however, only 30% demonstrate archetypical SCDS clinical proxies (Tullio or Hennebert findings). Several case-control studies have addressed specific SCDS markers using VEMP testing, but the diagnostic value of VEMP for SCDS has not been demonstrated in a target population of dizzy patients. The aim of this study was to confirm the diagnostic properties of oVEMP for SCDS in an unselected cohort of dizzy patients.
Design:
This diagnostic accuracy study was performed in a tertiary referral center and included a consecutive sample of dizzy patients referred for vestibular function testing. One hundred fifty subjects were collected prospectively; five were excluded due to middle ear disorders, 10 had the target condition (SCDS group), and 135 had an alternative condition (non-SCDS group), based on diagnostic criteria for SCDS used in our department as reference standard. The non-SCDS group was subdivided into diagnostic categories including an “undefined dizziness” group. The index test applied to the total sample (missing data: 1%) consisted of oVEMP recording using three different stimulation modalities, that is, air-conducted (AC) sound stimulation and midsagittal bone-conducted (BC) vibration at both forehead (Fz) and vertex (Cz). Data...

Source: Ear and Hearing - March 1, 2019 Category: Audiology Tags: Research Article Source Type: research