Multiple pairs of allelic MLA immune receptor-powdery mildew AVR < sub > A < /sub > effectors argue for a direct recognition mechanism

We report here the isolation ofBghAVRa7,AVRa9,AVRa10,andAVRa22, which encode small secreted proteins recognized by allelic MLA7, MLA9, MLA10, and MLA22 receptors, respectively. These effectors are sequence-unrelated, except for allelicAVRa10andAVRa22 that are co-maintained in pathogen populations in the form of a balanced polymorphism. Contrary to numerous examples of indirect recognition of bacterial effectors by plant NLRs, co-expression experiments with matchingMla-AVRa pairs indicate direct detection of the sequence-unrelated fungal effectors by MLA receptors.
Source: eLife - Category: Biomedical Science Tags: Plant Biology Source Type: research