DRAM2 acts as an oncogene in non-small cell lung cancer and suppresses the expression of p53.

CONCLUSIONS: DRAM2 plays an oncogenic role in NSCLC via regulating p53 expression. Therefore, DRAM2 may act as an oncogene in NSCLC and could serve as a prognostic factor and potential target for NSCLC treatment.
PMID: 30755245 [PubMed - in process]

Source: Clinical Lung Cancer - February 12, 2019 Category: Cancer & Oncology Authors: Wudu M, Ren H, Hui L, Jiang J, Zhang S, Xu Y, Wang Q, Su H, Jiang X, Dao R, Qiu X Tags: J Exp Clin Cancer Res Source Type: research