Unfit Teens Often Grow Into Sickly Middle Age, Study Shows

TUESDAY, Feb. 12, 2019 -- Teen boys who are unfit and/or obese have higher odds for chronic disease and disability as adults, according to a large Swedish study. Researchers followed more than 1 million boys for an average of 28 years, starting when...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news

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This study defines a new clinically relevant concept of T-cell senescence-mediated inflammatory responses in the pathophysiology of abnormal glucose homeostasis. We also found that T-cell senescence is associated with systemic inflammation and alters hepatic glucose homeostasis. The rational modulation of T-cell senescence would be a promising avenue for the treatment or prevention of diabetes. Intron Retention via Alternative Splicing as a Signature of Aging https://www.fightaging.org/archives/2019/03/intron-retention-via-alternative-splicing-as-a-signature-of-aging/ In recent years researchers have inv...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
AbstractThe World Health Organization defines overweight and obesity as the condition where excess or abnormal fat accumulation increases risks to health. The prevalence of obesity is increasing worldwide and is around 20% in ICU patients. Adipose tissue is highly metabolically active, and especially visceral adipose tissue has a deleterious adipocyte secretory profile resulting in insulin resistance and a chronic low-grade inflammatory and procoagulant state. Obesity is strongly linked with chronic diseases such as type 2 diabetes, hypertension, cardiovascular diseases, dyslipidemia, non-alcoholic fatty liver disease, chr...
Source: Intensive Care Medicine - Category: Intensive Care Source Type: research
Authors: Zhang S, Zhang W, Zhou G Abstract Stroke causes disability and high mortality, while it can be prevented by increasing public awareness of risk factors. The common known risk factors are hypertension, atrial fibrillation, heart failure, smoking, alcohol consumption, low physical activity, overweight and hypercholesterolemia. However, the deep understanding of risk factors is limited. Moreover, more risk factor emerges in recent years. To further increase the awareness of risk factors for stroke prevention, this review indicates the reasonable application of antihypertensive agents according to the age-depe...
Source: Journal of the National Medical Association - Category: General Medicine Tags: J Natl Med Assoc Source Type: research
Purpose Prader–Willi syndrome (PWS) is a complex, rare neurobehavioral syndrome characterized by excessive fat, hypotonia, poor motor skills, and behavioral and cognitive disabilities. We tested the effectiveness of a home-based physical activity (PA) intervention led by parents in youth with obesity with and without PWS to increase moderate-to-vigorous PA (MVPA) and gross motor proficiency. Methods Participants were 111 youth age 8 to 16 yr (45 with PWS and 66 without PWS, but categorized as obese). A parallel design was used with the control group (C) receiving the intervention after serving as control. Interv...
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: APPLIED SCIENCES Source Type: research
ConclusionsObese patients demonstrated lower functional performance compared with their non-obese counterparts, while cervical lordosis was diminished and the cSVA was increased in obese patients.Graphical abstractThese slides can be retrieved under Electronic Supplementary Material.
Source: European Spine Journal - Category: Orthopaedics Source Type: research
Publication date: Available online 12 March 2019Source: The LancetAuthor(s): Peter S Azzopardi, Stephen J C Hearps, Kate L Francis, Elissa C Kennedy, Ali H Mokdad, Nicholas J Kassebaum, Stephen Lim, Caleb M S Irvine, Theo Vos, Alex D Brown, Surabhi Dogra, Stuart A Kinner, Natasha S Kaoma, Mariam Naguib, Nicola J Reavley, Jennifer Requejo, John S Santelli, Susan M Sawyer, Vegard Skirbekk, Marleen TemmermanSummaryBackgroundRapid demographic, epidemiological, and nutritional transitons have brought a pressing need to track progress in adolescent health. Here, we present country-level estimates of 12 headline indicators from t...
Source: The Lancet - Category: General Medicine Source Type: research
Fitness is a problem for many people, not least special needs teens and adults. Diabetes and obesity are common in our population.Diet is a factor — it takes a lot of cognitive work to outrun the American junk food industry. The special needs population is vulnerable to deceptive advertising implying health benefits of " sports drinks " .Exercise is also a problem. Special Olympics and Special Hockey programs are low volume — typically once a week. Group classes may be intimidating or unwelcoming. Incomes are low and gyms can be costly [1]. Workout music may be intolerable. The feel and odor of sweat ...
Source: Be the Best You can Be - Category: Disability Tags: adult Asperger ' autism community exercise Source Type: blogs
Grants for projects designed to reduce rates of death and disability from commercial tobacco use, diabetes, heart disease, and stroke and reduce the prevalence of obesity and other chronic disease risk factors and conditions in American Indian and Alaska Native communities. Geographic coverage: Nationwide -- Centers for Disease Control and Prevention, U.S. Department of Health and Human Services
Source: Funding opportunities via the Rural Health Information Hub - Category: American Health Source Type: funding
Restaurants have been slow to recognize, much less meet, the needs of plus-size Americans. But there are signs of a new activism and awareness.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Restaurants Obesity Americans With Disabilities Act United States Alexander, Rebecca Source Type: news
Abstract Among chronic low back pain (CLBP) patients, workers' compensation is associated with longer term prescription opioid analgesic use (OAU). The aim was to study the association between receiving Social Security Disability Insurance (SSDI) benefits and course of OAU. This prospective cohort study utilized data from primary care patients diagnosed with non-cancer CLBP. The outcomes were morphine equivalent dose (MED) - categorized as no OAU, 1-50mg MED, or>50mg MED - and change in MED over time using mixed multinomial logistic regression models. Covariates included sociodemographics, pain severity, pain m...
Source: Pain Physician - Category: Anesthesiology Authors: Tags: Popul Health Manag Source Type: research
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