Nearly 20 years of migraines and the pain is still surprising

Can't see, can't speak, can't stop throwing up. The glamorous life of a woman with chronic migraines, writes Stephanie Tobin.
Source: CBC | Health - Category: Consumer Health News Tags: News/Canada/Nfld. & Labrador Source Type: news

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ConclusionCM patients have a stronger connectivity in the pain matrix than do EM patients. Functional alteration of the pain network might play a role in migraine chronification.
Source: The Journal of Headache and Pain - Category: Neurology Source Type: research
Pain catastrophizing plays a key role in shaping the experience of acute and chronic pain, adverse pain-related outcomes and amplified pain perception. Mindfulness-based stress reduction (MBSR) is an evidence-based program designed to focus attention on the present moment in order to decrease stress, and enhance overall wellbeing. MBSR is believed to benefit patients with chronic pain by increasing pain acceptance and potentially interrupting the link between cognitive and emotional experiences, such as catastrophizing, and the experience of pain.
Source: The Journal of Pain - Category: Materials Science Authors: Source Type: research
Erenumab is a calcitonin gene-related peptide (CGRP) monoclonal antibody, approved recently for prevention of episodic and chronic migraine. CGRP is involved in the pathogenesis of migraine, and erenumab works by blocking the CGRP receptors. Common side effects include injection site reactions and constipation. Here we present a patient with hemicrania continua (HC) who responded well to erenumab, while the medication additionally treated her debilitating diarrhea. A 61-year-old female with history of intractable, refractory, chronic, daily, left hemicranial headaches with migrainous features associated with restlessness, ...
Source: The Journal of Pain - Category: Materials Science Authors: Source Type: research
Post-traumatic headache (PTH) after traumatic brain injury (TBI) is debilitating and hard to diagnose. Unfortunately, PTH is highly prevalent in active duty personnel, Veterans, as well as in sport athletes. The high incidence and chronic nature of PTH underscores the need to study these problems in animal models in order to develop new and effective treatments. The foundation of our study is the fact that PTH has many symptoms of chronic migraine. We proposed to evaluate photosensitivity and tactile hypersensitivity in two mouse models of mild TBI: the blast-induced TBI model and the closed-head injury (mCHI) model induced by weight drop.
Source: The Journal of Pain - Category: Materials Science Authors: Source Type: research
Persistent post-traumatic headache (PTH) and chronic migraine (CM) often present with clinically overlapping features including prominent light sensitivity. Dynamic pupillometry is a promising new tool for evaluation of autonomically mediated responses to light in headache disorders, as they may differ between headache phenotypes. While our prior work has evaluated autonomic responses in chronic migraine and mild traumatic brain injury (aka concussion), differences in PTH and chronic migraine have not been explored.
Source: The Journal of Pain - Category: Materials Science Authors: Source Type: research
Conclusion: Pain severe enough to impact patients' daily lives is common in Vietnam. Treatment costs are a significant economic burden and may help explain why only a minority of patients seek treatment. Access to lower cost, effective treatment for pain should be improved. PMID: 30881090 [PubMed]
Source: Pain Physician - Category: Anesthesiology Authors: Tags: J Pain Res Source Type: research
Authors: Sakurai Y, Fujii A, Kato F Abstract Persistent idiopathic facial pain (PIFP) is a poorly understood chronic disorder that rarely occurs in children. An 11-year-old boy initially presented with right cheek pain and a streptococcal infection 6 weeks previously. Facial cellulitis was suspected, which was resolved by antibiotic treatment. The right cheek pain recurred within 4 weeks of this initial visit. Because the antibiotic treatment did not relieve the pain, the patient visited our outpatient clinic. Physical examination revealed facial tenderness in an area that corresponded with the region supplied by t...
Source: Case Reports in Psychiatry - Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research
AbstractHeadache is a milestone in cerebrovascular disorders; indeed, it may represent the only symptom at onset or predominates over the other neurological features. Unfortunately, headache associated with cerebrovascular diseases lacks clear-cut characteristics as it may resemble a migraine attack, tension-type headache, or cluster headache; pain localization is also misleading along with drug (analgesic) response. However, in this review, we have analyzed and described the most common patterns of headache for different vascular disorders: it is known that headache due to subarachnoid aneurysmal hemorrhage presents pecul...
Source: Neurological Sciences - Category: Neurology Source Type: research
ConclusionOur pilot work indicates that our intervention is feasible to deliver, and with the relevant changes would be acceptable for use with this population. Our randomised control trial is ongoing. We anticipate publishing final results in 2021.Trial registrationISRCTN79708100. Registered 16th December 2015,http://www.isrctn.com/ISRCTN79708100
Source: The Journal of Headache and Pain - Category: Neurology Source Type: research
AbstractPurpose of ReviewThe purpose of the present investigation is to summarize supporting evidence for novel sub-perception spinal cord stimulation (SCS) therapy over traditional paresthesia inducing low-frequency waveforms for the treatment of chronic pain. The focus of this review is to summarize key studies comparing traditional low-frequency tonic waveforms to modern high frequency and burst stimulation for the treatment of patients with chronic intractable low back pain and/or leg pain.Recent FindingsSeveral recent studies have demonstrated the benefit of novel SCS therapies over traditional low-frequency SCS for t...
Source: Current Pain and Headache Reports - Category: Neurology Source Type: research
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