'We're holding up a floodgate': B.C. fights off superbugs brought home by medical tourists

Health officials are warning travellers about the risk of contracting drug-resistant infections abroad, after two confirmed cases of an emerging superbug were found at Royal Columbian Hospital.
Source: CBC | Health - Category: Consumer Health News Tags: News/Canada/British Columbia Source Type: news

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We describe the investigation and management of an MRSA outbreak on a neonatal intensive care unit (NICU) and the lessons learnt.Study designOutbreak report and case-control study.Study setting and participants: The study was conducted in a 40-cot NICU in a tertiary referral hospital and included all infants colonised/infected with gentamicin-resistant MRSA.InterventionsStandard infection control measures including segregation of infants, barrier precautions, enhanced cleaning, assessment of staff practice including hand hygiene, and increased MRSA screening of infants were implemented. Continued MRSA acquisitions led to s...
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research
According to this study: Decolonization with chlorhexidine and mupirocin led to lower risks of postdischarge methicillin-resistant Staphylococcus aureus and readmission compared with hygiene education alone.
Source: AJN - Category: Nursing Tags: Journal Watch Source Type: research
In this study, we evaluated the antimicrobial activity of the extracts from herbal plant Persecaria pensylvanicum’s flower, leaf, stem and root. This plant is also known by a common name Pennsylvania smartweed. The antimicrobial effect of the extracts was tested using minimimum inhibitory concentration (MIC) and minimum bacteriocidal concentration (MBC) methods in comparison with tetracycline, a commercial antibiotic.ResultsWe found that extract from P. pensylvanicum kills bovine mammary glands pathogenic S. aureus strain Newbould 305. The minimum inhibitory concentration (MIC) breakpoints for extracts from flower, l...
Source: European Journal of Integrative Medicine - Category: Complementary Medicine Source Type: research
WHO Africa’s Matshidiso Moeti, abortion rows, superbug jitterbug
Source: FT.com - Drugs and Healthcare - Category: Pharmaceuticals Source Type: news
ConclusionsThe developed formulations demonstrated promising in ‐vivo biocompatibility and antibacterial efficacy, signifying their potential application as ophthalmic preparation to overcome ocular infections induced by resistant bacterial strains while minimizing drug irritation and improving patient compliance.
Source: Journal of Pharmacy and Pharmacology - Category: Drugs & Pharmacology Authors: Tags: Research Paper Source Type: research
Reports of methicillin-resistant Staphylococcus aureus (MRSA) harboring the mecC gene have increased in the UK since first being described. To our diagnostic S. aureus multiplex PCR, a mecC primer set was designed and implemented, and then the prevalence in our patient population was investigated. Fewer than 1% of the clinical isolates possessed the mecC gene, confirming that mecA remains the dominant genetic determinant of MRSA in East London.
Source: Journal of Clinical Microbiology - Category: Microbiology Authors: Tags: Bacteriology Source Type: research
There is growing evidence for the value of bacterial whole-genome sequencing in hospital outbreak investigations. Our aim was to develop methods that support efficient and accurate low-throughput clinical sequencing of methicillin-resistant Staphylococcus aureus (MRSA) isolates. Using a test panel of 25 MRSA isolates previously associated with outbreak investigations, we devised modifications to library preparation that reduced the processing time by 1 hour. We determined the maximum number of isolates that could be sequenced per run using an Illumina MiniSeq platform and a 13-hour (overnight) run time, which equated to 21...
Source: Journal of Clinical Microbiology - Category: Microbiology Authors: Tags: Bacteriology Source Type: research
Scientists have discovered yet another way that single-celled organisms have outsmarted us.The tiny bacteria that live inside our guts have an ingenious way of withstanding the onslaught of antibiotics we throw at them, according to a report published Thursday in the journalScience. The two-part...
Source: Los Angeles Times - Science - Category: Science Authors: Source Type: news
Conclusions: Our findings suggest the need for a comprehensive, multipronged policy response particularly at the time when the antibiotic pipeline is nearly empty. We recommend thoughtful, integrated infection prevention and control strategies to address the immediate and long-term threats of AR in Bahrain and the GCC. PMID: 31110624 [PubMed]
Source: Oman Medical Journal - Category: Middle East Health Tags: Oman Med J Source Type: research
This study aimed to determine the dynamics of colonization with antimicrobial-resistant Gram-negative bacteria amongst patients in a neonatal intensive care unit (NICU) in Thailand. From 97 enrolled patients, 52% were colonized by an extended-spectrum β-lactamase (ESBL) organism at some point during their stay and 64% were colonized by a carbapenem-resistant organism. Rapid acquisition of ESBL-positive and carbapenem-resistant organisms was found. Once colonized with an antibiotic-resistant organism, patients remained colonized for the remainder of their NICU stay.
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research
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