The endothelial glycocalyx: Barrier functions versus red cell hemodynamics: A model of steady state ultrafiltration through a bi-layer formed by a porous outer layer and more selective membrane-associated inner layer.

CONCLUSIONS:  The model places significant constraints on the outer layer permeability properties . The only outer layer properties that are consistent with measured steady state filtration rates and models of red cell flux through microvessels are an albumin permeability coefficient and hydraulic conductivity more than an order of magnitude larger than the those of the inner layer.
PMID: 30664499 [PubMed - as supplied by publisher]

Source: Biorheology - January 23, 2019 Category: Biochemistry Tags: Biorheology Source Type: research