Usefulness of whole blood viscosity estimated by de Simeone's formula to predict left ventricular thrombus formation within one year following acute anterior myocardial infarction.
CONCLUSION: As an easily accessible parameter, WBV might be a useful predictor of LVT formation within one year following acute anterior myocardial infarction. PMID: 32444531 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - May 25, 2020 Category: Biochemistry Tags: Biorheology Source Type: research

Porcine bile viscosity is proportional to density.
CONCLUSIONS: Porcine bile viscosity is proportional to density. Based on the bile density, one can easily evaluate the shear viscosity using a linear relationship. The density considerably influences the bile viscosity, with small density increases greatly increasing the shear viscosity. PMID: 32333577 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - April 26, 2020 Category: Biochemistry Tags: Biorheology Source Type: research

Viscoelastic behavior of cardiomyocytes carrying LMNA mutations.
CONCLUSIONS: These features resulted from a combination of the properties of cytoskeleton filaments and their temporary cross-linker. Our results substantiate that cross-linked filaments contribute, for the most part, to the mechanical strength of the cytoskeleton of the cell studied and the relaxation time is determined by the dissociation dynamics of the cross-linking proteins. The severity of biomechanical defects due to these LMNA mutations correlated with the severity of the clinical phenotype. PMID: 32083564 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - February 24, 2020 Category: Biochemistry Tags: Biorheology Source Type: research

Viscoelastic characterization of diabetic and non-diabetic human adipose tissue.
CONCLUSION: Although DM is typically associated with adipose tissue fibrosis, it is not associated with differences in macroscopic adipose tissue mechanical properties. PMID: 32083565 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - February 24, 2020 Category: Biochemistry Tags: Biorheology Source Type: research

Preface.
Authors: Lipowsky H PMID: 31796659 [PubMed - in process] (Source: Biorheology)
Source: Biorheology - December 6, 2019 Category: Biochemistry Tags: Biorheology Source Type: research

Relative shedding of glycosaminoglycans from the endothelial glycocalyx during inflammation and their contribution to stiffness of the glycocalyx.
CONCLUSIONS: The relatively rapid shedding of HA compared to HS was consistent with the hypothesis that HA may form the dominant barrier to WBC-EC adhesion. Prior observations that HA lies closer to and parallel to the endothelial membrane, compared to HS suggests that the compact layer of HA near the EC membrane surrounds WBC adhesion receptors that are much shorter in length than the total thickness of the glycocalyx. The relatively low elastic modulus of the glycocalyx under shear is consistent with the hypothesis that the FLMs adhered to strands of HS normal to the EC surface that extended above the relatively more com...
Source: Biorheology - November 11, 2019 Category: Biochemistry Tags: Biorheology Source Type: research

Nitrite may serve as a combination partner and a biomarker for the anti-cancer activity of RRx-001.
Authors: Cirrik S, Ugurel E, Aksu AC, Oronsky B, Cabrales P, Yalcin O Abstract BACKGROUND: RRx-001 is an anti-cancer immunotherapeutic that increases the sensitivity of drug resistant tumors via multiple mechanisms which involve binding to hemoglobin and enhancing nitrite reductase activity of deoxyhemoglobin. OBJECTIVE: In the present study, the effect of clinically used doses of RRx-001 on erythrocyte deformability was examined. METHODS: A dose dependent effect of RRx-001 (1-1000 micro molar) on erythrocyte deformability was measured by ektacytometer under hypoxia (n = 8). Low dose RRx-001 (20 micro ...
Source: Biorheology - October 25, 2019 Category: Biochemistry Tags: Biorheology Source Type: research

Mechanobiology of the abluminal glycocalyx.
CONCLUSIONS: While requiring experimental verification, this analysis supports the hypothesis that shear on the luminal surface can be transmitted to the abluminal surface and deform the cell in the vicinity of the focal adhesions, with the magnitude of deformation depending on the abluminal glycocalyx modulus. PMID: 31561318 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - September 30, 2019 Category: Biochemistry Tags: Biorheology Source Type: research

Correlation of the cell mechanical behavior and quantified cytoskeletal parameters in normal and cancerous breast cell lines.
CONCLUSIONS: Results of this study confirmed that alterations in cell mechanical properties induced by cancer are highly correlated with changes in F-actin and microtubule content and arrangement. It is suggested that such changes can enhance our knowledge of cancer initiation and progression. PMID: 31561319 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - September 30, 2019 Category: Biochemistry Tags: Biorheology Source Type: research

Tensile behavior and extensional viscosity of bile.
CONCLUSIONS: The extensional viscosity of bile is much greater than its shear viscosity. Because mucus concentration makes bile sediment more viscous than the solution, bile viscosity can increase sharply, thereby increasing risks of such diseases as gallstones and sludge buildup in the biliary system. PMID: 31561320 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - September 30, 2019 Category: Biochemistry Tags: Biorheology Source Type: research

Effect of arterial curvature on hemodynamics and mass transport.
CONCLUSIONS: Under the same flow rate, a larger bend angle increased flow resistance, lowered WSS, and increased LDL surface concentrations, thus indicating an increased risk of atherosclerosis. PMID: 31282391 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - July 10, 2019 Category: Biochemistry Tags: Biorheology Source Type: research

The cancer cell glycocalyx proteoglycan glypican-1 mediates interstitial flow mechanotransduction to enhance cell migration and metastasis.
CONCLUSIONS: Glypican-1 provides the mechanical linkage from HS (the flow sensor) to the SN12L1 cell where mechanotransduction leading to the enhancement of migration (metastasis) occurs. MAPKs downstream of Glypican-1 propagate the signal. The HS, Glypican-1, MAPK signaling axis suggests opportunities for pharmaceutical intervention. PMID: 31256115 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - July 2, 2019 Category: Biochemistry Tags: Biorheology Source Type: research

Endothelial glycocalyx restoration by growth factors in diabetic nephropathy.
Authors: Desideri S, Onions KL, Baker SL, Gamez M, El Hegni E Hussien H, Russel A, Satchell SC, Foster RR Abstract The endothelial glycocalyx (eGlx) constitutes the first barrier to protein in all blood vessels. This is particularly noteworthy in the renal glomerulus, an ultrafiltration barrier. Leakage of protein, such as albumin, across glomerular capillaries results in albumin in the urine (albuminuria). This is a hall mark of kidney disease and can reflect loss of blood vessel integrity in microvascular beds elsewhere. We discuss evidence demonstrating that targeted damage to the glomerular eGlx results in incr...
Source: Biorheology - June 5, 2019 Category: Biochemistry Tags: Biorheology Source Type: research

Numerical investigation of the effects of blood rheology and wall elasticity in abdominal aortic aneurysm under pulsatile flow conditions.
CONCLUSIONS: Newtonian assumption for the blood as well as modelling the arterial wall as linearly elastic lead to significant differences in oscillatory hemodynamic properties with respect to the use of Carreau fluid together with hyperelastic vessel model, even in large vessel aneurysms. PMID: 31045509 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - May 4, 2019 Category: Biochemistry Tags: Biorheology Source Type: research

Endothelial surface glycocalyx (ESG) components and ultra-structure revealed by stochastic optical reconstruction microscopy (STORM).
CONCLUSIONS: Our results suggest that HS plays a major role in mechanosensing and HA plays a major role in the molecular sieve. PMID: 31045510 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - May 4, 2019 Category: Biochemistry Tags: Biorheology Source Type: research

Endothelial barrier reinforcement relies on flow-regulated glycocalyx, a potential therapeutic target.
CONCLUSIONS: Regenerating the degraded GCX reverses EC barrier dysfunction and may attenuate the progression of vascular disease. PMID: 30988234 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - April 17, 2019 Category: Biochemistry Tags: Biorheology Source Type: research

Blood flow distribution and the endothelial surface layer in the diabetic retina.
Authors: Harris NR, Leskova W, Kaur G, Eshaq RS, Carter PR Abstract Diabetic retinopathy is known as a microvascular complication of hyperglycemia, with a breakdown of the blood-retinal barrier, loss of pericytes, formation of microhemorrhages, early decreases in perfusion and areas of ischemia, with the latter speculated to induce the eventual proliferative, angiogenic phase of the disease. Our animal models of diabetic retinopathy demonstrate similar decreases in retinal blood flow as seen in the early stages of diabetes in humans. Our studies also show an alteration in the retinal distribution of red blood cells...
Source: Biorheology - April 10, 2019 Category: Biochemistry Tags: Biorheology Source Type: research

Rheological properties and efficacy of the formulation of hyaluronic acid with tamarind seed polysaccharide for arthritis.
CONCLUSIONS: TSP is a potential material as a substitute for HA or in combination with HA for intra-articular injection for arthritis. PMID: 30909181 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - March 27, 2019 Category: Biochemistry Tags: Biorheology Source Type: research

Understanding endothelial glycocalyx function under flow shear stress from a molecular perspective.
CONCLUSIONS: This study relates the functions of the glycocalyx with its microscopic dynamics, which fills a knowledge gap about the links between different scales. PMID: 30856098 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - March 13, 2019 Category: Biochemistry Tags: Biorheology Source Type: research

Shear-thickening fluids in biologically relevant agents.
CONCLUSIONS:  This study established that shear thickening is compatible with cryobiologically relevant agents, particularly so at lower temperatures. This forms the basis for harnessing these phenomena in biological processes such as cryopreservation. PMID: 30814341 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - March 4, 2019 Category: Biochemistry Tags: Biorheology Source Type: research

Microvascular hemodynamics: System properties1.
Authors: Pries AR Abstract The hemodynamics of the microcirculation reflect system properties of the involved components. The blood itself is a complex suspension of water, small and large molecules and different cell types. Under most conditions, its rheologic properties are dominated by the different behaviour of fluid and cellular compartments. When perfused through small-bore tubes or vessels, the suspension exhibits specific emergent properties. The Fahraeus-effect and the Fahreaeus-Lindqvist-effect result from the interaction of cellular particles with each other and with the vessel wall. Additional phenomena...
Source: Biorheology - March 4, 2019 Category: Biochemistry Tags: Biorheology Source Type: research

Comparative adhesive and migratory properties of mesenchymal stem cells from different tissues.
CONCLUSIONS: MSC show origin-dependent variations in their efficiency of capture from flow and subsequent spreading or ability to migrate on matrix proteins. UCMSC showed most efficient capture from flow, which was followed by less spreading, but more rapid migration. These responses might be associated with more effective delivery from the circulation into damaged tissue. PMID: 30714948 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - February 5, 2019 Category: Biochemistry Tags: Biorheology Source Type: research

The endothelial glycocalyx: Barrier functions versus red cell hemodynamics: A model of steady state ultrafiltration through a bi-layer formed by a porous outer layer and more selective membrane-associated inner layer.
CONCLUSIONS:  The model places significant constraints on the outer layer permeability properties . The only outer layer properties that are consistent with measured steady state filtration rates and models of red cell flux through microvessels are an albumin permeability coefficient and hydraulic conductivity more than an order of magnitude larger than the those of the inner layer. PMID: 30664499 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - January 23, 2019 Category: Biochemistry Tags: Biorheology Source Type: research

Rheological parameters of saliva in comparison with taste examination.
CONCLUSIONS: Saliva viscosity was found to decrease with increasing shear rate and varied with time. Analysis of the dependence of the viscosity values of saliva and components of complex viscosity did not show a significant correlation with taste sensation. A dependency of taste sensation on pH could not be discerned due to the narrow range of naturally occurring pH. PMID: 30530953 [PubMed - in process] (Source: Biorheology)
Source: Biorheology - December 13, 2018 Category: Biochemistry Tags: Biorheology Source Type: research

Increased erythrocyte aggregation following an acute bout of eccentric isokinetic exercise does not exceed two days.
CONCLUSION: Our results suggest that, increased RBC aggregation following an acute bout of isokinetic exercise may result in increased plasma skimming that augments tissue perfusion and clearance of metabolites within a period of two days following exercise. PMID: 30530954 [PubMed - in process] (Source: Biorheology)
Source: Biorheology - December 13, 2018 Category: Biochemistry Tags: Biorheology Source Type: research

Characterization of the visco-elastic properties of hyaluronic acid.
CONCLUSIONS: The viscoelastic properties of the HA preparations can be ordered according to the values of G∗ (the rigidity, or vector sum of the elastic modulus G' and the viscous modulus G'') at both transition points (0.5 and 2.5 Hz) as follows: Viscoplus_Matrix®> Viscoplus_Gel®> Durolane®> Synocrom_Forte_One®> Ostenil_Plus®> Synvisc_One®> Orthovisc®> Ostenil®. PMID: 30320557 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - October 17, 2018 Category: Biochemistry Tags: Biorheology Source Type: research

Depletion-model-based numerical simulation of the kinetics of red blood cell aggregation under sinusoidal pulsatile flow.
CONCLUSIONS: The present simulation results verified previous experimental results and improved the current understanding of the complex spatiotemporal changes experienced by RBC aggregates during a sinusoidal pulsatile cycle. PMID: 30010095 [PubMed - in process] (Source: Biorheology)
Source: Biorheology - July 18, 2018 Category: Biochemistry Tags: Biorheology Source Type: research

Biomechanical properties of veins cultured in vitro under elevated internal pressure.
CONCLUSIONS: The in vitro results were essentially similar to those obtained from previous in vivo animal experiments, indicating that in vitro tissue culture techniques are applicable to studies of venous remodeling. PMID: 30010096 [PubMed - in process] (Source: Biorheology)
Source: Biorheology - July 18, 2018 Category: Biochemistry Tags: Biorheology Source Type: research

Rheological characterization of an in vitro model for salmonid chyme to quantify changes in feed composition.
CONCLUSIONS: These data open a new statistical approach to monitoring the consequences of market-driven changes in aqua feed composition and their impacts on the nutrition, health or performance of farmed fish. PMID: 29660895 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - April 19, 2018 Category: Biochemistry Tags: Biorheology Source Type: research

Cross-sectional distributions of normal and abnormal red blood cells in capillary tubes determined by a new technique.
CONCLUSIONS: The newly devised observation system revealed quantitatively the essential role of RBC deformability in their axial accumulation. PMID: 29614620 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - April 6, 2018 Category: Biochemistry Tags: Biorheology Source Type: research

Effects of aging and gender on micro-rheology of blood in 3 to 18 months old male and female Wistar (Crl:WI) rats.
CONCLUSIONS: The micro-rheological parameters showed age-related alterations with gender differences. The effect of the estrous cycle cannot be excluded in female rats. The results provide reference data for studies of aging in rats and of the mechanism related to age and gender differences in hemorheology. PMID: 29562483 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - March 27, 2018 Category: Biochemistry Tags: Biorheology Source Type: research

Recovery time course of erythrocyte deformability following exposure to shear is dependent upon conditioning shear stress.
CONCLUSION: Specific shear conditioning results in either temporarily increased cell deformability, or a less reversible decrease of RBC deformability. PMID: 29578460 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - March 27, 2018 Category: Biochemistry Tags: Biorheology Source Type: research

Articular cartilage response to a sliding load using two different-sized spherical indenters1.
CONCLUSION: Sliding loads that increase ECM deformation/strain were found to induce enzyme-mediated catabolic processes in articular cartilage explants. These observations provide further understanding of how changes in cartilage contact mechanics under dynamic conditions can affect the cellular response. PMID: 29376845 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - January 31, 2018 Category: Biochemistry Tags: Biorheology Source Type: research

Remodeling of the arterial wall: Response to restoration of normal blood flow after flow  reduction.
CONCLUSIONS: Arteries change diameters in response to BF reduction and also flow restoration to normal after flow reduction, keeping WSS at physiologically normal levels. The lack of changes in vascular elasticity suggests that there were no significant changes in major wall constituents, such as elastin and collagen, and thus VSM may play the dominant role in observed arterial remodeling and adaptation. PMID: 29376846 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - January 31, 2018 Category: Biochemistry Tags: Biorheology Source Type: research

In vitro measurement of platelet adhesion to intact endothelial cells under low shear conditions.
CONCLUSIONS: The number of adherent platelets is determined by a balance between the shear and the degree of stimulation by the agonist. At an ADP concentration of 1 µM, a limit to the shear rate at which platelets can adhere to intact endothelial cells is considered to be slightly higher than 16.8 s-1. PMID: 29355112 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - January 23, 2018 Category: Biochemistry Tags: Biorheology Source Type: research

Possible erythrocyte contributions to and exacerbation of the post-thrombolytic no-reflow phenomenon.
CONCLUSION: Findings demonstrated that post-lytic changes in red cell deformability do occur which could contribute to the no-reflow phenomenon. PMID: 29332028 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - January 16, 2018 Category: Biochemistry Tags: Biorheology Source Type: research

Linear rheology as a potential monitoring tool for sputum in patients with Chronic Obstructive Pulmonary Disease (COPD).
Authors: Nettle CJ, Jenkins L, Curtis D, Badiei N, Lewis K, Williams PR, Daniels DR Abstract Sputum samples from Chronic Obstructive Pulmonary Disease (COPD) patients were investigated using rheology, simple mathematical modelling and Scanning Electron Microscopy (SEM). The samples were all collected from patients within two days of their admission to Prince Philip Hospital due to an exacerbation of their COPD. Oscillatory and creep rheological techniques were used to measure changes in viscoelastic properties at different frequencies over time, and COPD sputum was observed to behave as a viscoelastic solid at all ...
Source: Biorheology - December 29, 2017 Category: Biochemistry Tags: Biorheology Source Type: research

Simultaneous assessment of blood coagulation and hematocrit levels in dielectric blood coagulometry.
CONCLUSIONS: Changes in the hematocrit level may affect whole blood coagulation tests. DBCM has the potential to overcome this effect with some automated correction using results from simultaneous evaluations of the hematocrit level and blood coagulability. PMID: 28800301 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - August 12, 2017 Category: Biochemistry Tags: Biorheology Source Type: research

Impact of training volume and intensity on RBC-NOS/NO pathway and endurance capacity.
CONCLUSIONS: High intensity training was the only training programme that sustainably affected RBC-NOS dependent NO production and performance capacity. HIT therefore represents a time efficient training program resulting in improved RBC function potentially improving physical condition. PMID: 28697553 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - July 13, 2017 Category: Biochemistry Tags: Biorheology Source Type: research

Author Index Volume 53 (2016).
Authors: PMID: 28372261 [PubMed - in process] (Source: Biorheology)
Source: Biorheology - April 7, 2017 Category: Biochemistry Tags: Biorheology Source Type: research

Effect of ovariectomy and Sideritis euboea extract administration on large artery mechanics, morphology, and structure in middle-aged rats.
CONCLUSIONS: Carotid artery remodeling in OVX rats was largely consistent with hypertensive remodeling, despite the minor arterial pressure changes found, and was not altered by administration of SID, despite previous evidence of its osteo-protective effect. PMID: 28339395 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - March 27, 2017 Category: Biochemistry Tags: Biorheology Source Type: research

The autodigestion hypothesis: Proteolytic receptor cleavage in rheological and cardiovascular cell dysfunction1.
Authors: Schmid-Schönbein GW Abstract Transformation of circulating leukocytes from a dormant into an activated state with changing rheological properties leads to a major shift of their behavior in the microcirculation. Low levels of pseudopod formation or expression of adhesion molecules facilitate relatively free passage through microvessels while activated leukocytes with pseudopods and enhanced levels of adhesion membrane proteins become trapped in microvessels, attach to the endothelium and migrate into the tissue. The transformation of leukocytes into an activated state is seen in many diseases. While m...
Source: Biorheology - March 10, 2017 Category: Biochemistry Tags: Biorheology Source Type: research

Creep compliance rheology with a probe-like cylindrical geometry.
Authors: Connelly K, Sharif-Kashani P, Farajzadeh M, Hubschman JP, Kavehpour HP Abstract BACKGROUND: Rheology experiments have been performed on the vitreous humor, a soft gel that rests inside of the eye, to study its viscoelastic behavior and underlying macromolecular structure. A significant challenge for experimentalists is preserving the macromolecular structure when removing vitreous from in vivo conditions. OBJECTIVE: We have developed a novel probe-like rheometer geometry that allows us to perform shear rheology experiments on the vitreous humor in situ. The aim of this study is to assess the feasibilit...
Source: Biorheology - February 24, 2017 Category: Biochemistry Tags: Biorheology Source Type: research

Prediction of the level and duration of shear stress exposure that induces subhemolytic damage to erythrocytes.
Authors: Simmonds MJ, Meiselman HJ Abstract BACKGROUND: Current generation mechanical circulatory assist devices are designed to minimize high shears to blood for prolonged durations to avoid hemolysis. However, red blood cells (RBC) demonstrate impaired capacity to deform when exposed to shear stress (SS) well below the "hemolytic threshold". OBJECTIVE: We endeavored to identify how changes in the magnitude and duration of SS exposure alter RBC deformability and subsequently develop a model to predict erythrocyte subhemolytic damage. METHODS: RBC suspensions were exposed to discrete magnitudes of...
Source: Biorheology - February 24, 2017 Category: Biochemistry Tags: Biorheology Source Type: research

Viscoelastic properties of normal rat liver measured by ultrasound elastography: Comparison with oscillatory rheometry.
CONCLUSIONS: The results indicate that the high frequency components of the dispersive data play a much more important role in determining the dispersive pattern or the viscous value than the low frequency components. It was found that the Maxwell model is not as appropriate as the Voigt and Zener models for describing the rheological behavior of liver. PMID: 27858670 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - November 20, 2016 Category: Biochemistry Tags: Biorheology Source Type: research

Effect of circulating tissue factor on hypercoagulability in type 2 diabetes mellitus  studied by rheometry and dielectric blood coagulometry.
CONCLUSIONS: Circulating TF is at least partially responsible for a hypercoagulable group of T2DM patients, while an abnormality in the intrinsic coagulation pathway probably occurs in the other group. PMID: 27858671 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - November 20, 2016 Category: Biochemistry Tags: Biorheology Source Type: research

Osteoarthritic synovial fluid rheology and correlations with protein concentration.
CONCLUSIONS: Increased protein concentration has been correlated with decreased shear rheological parameters. Temperature dependence of synovial fluid was also demonstrated and modelled for use in Part 2 of this article. PMID: 27767960 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - October 22, 2016 Category: Biochemistry Tags: Biorheology Source Type: research

Osteoarthritic synovial fluid and correlations with protein concentration.
CONCLUSIONS: Appropriate CaBER operating parameters for study of osteoarthritic synovial fluid were identified. No statistically significant correlation was found to exist between protein concentration and extensional rheological parameters. Positive correlations were identified between several shear and extensional rheological parameters. The reported values for extensional viscosity and relaxation times for synovial fluid were found to be within one order of magnitude with a recent study of post mortem synovial fluid. PMID: 27767961 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - October 22, 2016 Category: Biochemistry Tags: Biorheology Source Type: research

Biphasic impairment of erythrocyte deformability in response to repeated, short duration exposures of supraphysiological, subhaemolytic shear stress.
CONCLUSIONS: Repeat applications of short duration supraphysiological, subhaemolytic shear stress induces a biphasic RBC deformability response that appears to progressively improve initially impaired RBC populations. PMID: 27662271 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - September 24, 2016 Category: Biochemistry Tags: Biorheology Source Type: research

The effect of acute and short term normobaric hyperoxia on hemorheologic  parameters.
CONCLUSION: The results of the study suggest that application of normobaric hyperoxia does not have detrimental effects on hemorheological parameters in brain death patients, and that organs considered for donation from such subjects are not adversely affected by abnormalities of blood flow and tissue perfusion. PMID: 27567747 [PubMed - as supplied by publisher] (Source: Biorheology)
Source: Biorheology - August 30, 2016 Category: Biochemistry Tags: Biorheology Source Type: research