Is the Tpeak-Tend interval as a measure of repolarization heterogeneity dead or just seriously wounded?

This commentary relates to the article by Srinivasan et al [1], who studied relationships between intracardiac ventricular repolarization in normal human hearts in situ and the T-wave in the body surface ECG. They report not only that the slope of the T-wave upstroke in frontal precordial leads relates to repolarization differences between left and right ventricles but also that they found no meaningful relationship between myocardial repolarization heterogeneity, measured as differences in apicobasal, right-left ventricular, and transmural repolarization times, and duration of the Tpeak-Tend (Tpe) interval.

Source: Heart Rhythm - January 17, 2019 Category: Cardiology Authors: Marek Malik, Heikki V. Huikuri, Federico Lombardi, Georg Schmidt, Richard L. Verrier, Markus Zabel, e-Rhythm group of EHRA Source Type: research