Structures and biological activities of new carnosic acid- and carnosol-related compounds generated by heat treatment of rosemary

We examined their antioxidant activities and found that 2 and 3 showed strong activity. Furthermore, in PPARγ−transactivation and adipocyte-differentiation assays, compounds 3 and 5 showed more potent PPARγ agonistic activity than CA.Graphical abstract
Source: Phytochemistry Letters - Category: Chemistry Source Type: research