Indirect Treatment Comparisons and Biologics

Publication date: January 2019Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 7, Issue 1Author(s): David Mauger, Andrea J. Apter
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research

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The National Institutes of Health (NIH) would receive $34.4 billion in FY 2020, roughly $4.7 billion or 13 percent below the levels enacted by Congress for FY 2019, according to the President’s Budget released on March 11. The budget for NIH includes $492 million in funding made available through the 21st Century Cures Act and $150 million in mandatory funding. The leading biomedical research agency in the world would receive budget cuts across the board. All NIH centers are slated for budget reductions: National Cancer Institute: -8.7 percent National Heart, Lung, and Blood Institute: -14 percent National Inst...
Source: Public Policy Reports - Category: Biology Authors: Source Type: news
The rising prevalence of allergies represents an increasing socioeconomic burden. A detailed understanding of the immunological mechanisms that underlie the development of allergic disease, as well as the processes that drive immune tolerance to allergens, will be instrumental in designing therapeutic strategies to treat and prevent allergic disease. Improved characterization of individual patients through the use of specific biomarkers and improved definitions of disease endotypes are paving the way for the use of targeted therapeutic approaches for personalized treatment. Allergen-specific immunotherapy and biologic ther...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
AbstractInhaled mometasone was shown to improve pain scores and decrease soluble vascular cell adhesion molecule (sVCAM) concentration in a randomized controlled trial of nonasthmatic patients with sickle cell disease. We sought to explore potential changes in systemic inflammation as a mechanism underlying this effect. Serum samples from 41 trial participants (15 placebo- and 26 mometasone-treated) were analyzed using a 92 inflammatory marker panel at baseline and after 8  weeks of mometasone therapy. Individual marker analysis and correlation analysis were conducted. Adjusted for age, the mometasone-treated group de...
Source: Annals of Hematology - Category: Hematology Source Type: research
Publication date: Available online 17 March 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Ann Marie Mojica, Araceli Elizalde
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Although experts had advised parents in the past to avoid highly allergenic foods early in their child’s life, more recent research has suggested that early exposure to these foods might be a better option.
Source: WebMD Health - Category: Consumer Health News Source Type: news
' What distinguishes ENDO from other meetings is that you get a curated view of what is the newest, hottest, and best in science, which you going to be impacting care. 'Medscape Medical News
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Diabetes & Endocrinology News Source Type: news
(MedPage Today) -- Also new evidence on breastfeeding and atopic disease
Source: MedPage Today Allergy - Category: Allergy & Immunology Source Type: news
Giving a baby a new food to try is fun, and it should be. The only concerns parents should have: finding their phones fast enough to document the funny faces and cleaning up the mess that might follow. Yet in recent years, scientific evidence has accumulated quickly on what foods to introduce when and how to best prevent allergies -- leaving parents to keep track of it all.
Source: - Health - Category: Consumer Health News Source Type: news
Overall, 92.8 percent of oral solid medications contain at least one potential allergen
Source: The Doctors Lounge - Psychiatry - Category: Psychiatry Tags: Cardiology, Dermatology, Endocrinology, Family Medicine, Geriatrics, Gastroenterology, Gynecology, Infections, AIDS, Internal Medicine, Allergy, Critical Care, Emergency Medicine, Nephrology, Neurology, Nursing, Oncology, Ophthalmology, Orthopedics, ENT, Source Type: news
Introducing peanuts early may help some babies avoid allergies, according to new guidance from the American Academy of Pediatrics (AAP). The guidelines, published in the journal Pediatrics, update and replace the AAP’s 2008 report on preventing atopic diseases — such as asthma, skin conditions and food allergies — in children. While the science in this area is still developing, the AAP’s new report says that there is more evidence than ever to suggest that purposefully introducing some foods to children early in life may help prevent them from developing food allergies, which affect about 8% of Amer...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Research Source Type: news
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