Development of a Multifunctionalized Vascular Scaffolding System to Induce In Situ Endothelialization

Vascular tissue engineered grafts are one of the most promising alternatives to small-diameter prosthetic grafts, which often require reintervention within a decade of use. Previous methods of seeding vascular grafts with autologous patient cells have been successful; however, grafts constructed through these methods require copious amounts of preparation time before implantation. The growth or deposition of endothelial cells (ECs) onto the luminal surface of the prosthetic vessel may be critical for optimal physiological integration of a vascular scaffold to the host environment.
Source: Journal of Vascular Surgery - Category: Surgery Authors: Tags: Abstract from the 2019 Southern Association for Vascular Surgery Annual Meeting Source Type: research