Natural APOBEC3C variants can elicit differential HIV-1 restriction activity

The APOBEC3 (A3) family of DNA cytosine deaminases provides an innate barrier to infection by retroviruses including HIV-1. A total of five enzymes, A3C, A3D, A3F, A3G and A3H, are degraded by the viral access...

Source: Retrovirology - December 17, 2018 Category: Virology Authors: Brett D. Anderson, Terumasa Ikeda, Seyed Arad Moghadasi, Amber St. Martin, William L. Brown and Reuben S. Harris Tags: Research Source Type: research