Methodological considerations for large-scale breath analysis studies: lessons from the U-BIOPRED severe asthma project

In this study we use breath sample data from the recent U-BIOPRED cohort to evaluate and
discuss some important methodological considerations such as batch variation and correction,
variation between sites, storage and transportation, as well as inter-instrument analytical
differences. Based on this we provide a summary of recommended best practices for new large scale
multi-site studies.

Source: Journal of Breath Research - October 30, 2018 Category: Respiratory Medicine Authors: Waqar M Ahmed, Paul Brinkman, Hans Weda, Hugo H Knobel, Yun Xu, Tamara M Nijsen, Royston Goodacre, Nicholas Rattray, Teunis J Vink, Marco Santonico, Giorgio Pennazza, Paolo Montuschi, Peter J Sterk, Stephen J Fowler and on behalf of the U-BIOPRED study gr Source Type: research