GSE123410 RNA-seq data for non-targeting siRNA and CDK11 siRNA transfection in SHhES8 cells

Contributors : Jianyi Ding ; Ying JinSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensWe found that CDK11 KD in hESCs caused hESC differentiation. To get the detailed mechanism why its KD caused differentiation, we applied RNA-seq analysis, aiming to find out some clues about the mechanism. Firstly, we obtained the differentially expressed genes (DEGs) from NC and CDK11 KD hESC cells, replicated NC and 2 sets of CDK11 siRNA were transfected into SHhES8 cells for 4 days. Later, we analyzed the data and used GO analysis to enrich GO terms which might be helpful for our research.

Source: GEO: Gene Expression Omnibus - December 7, 2018 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research