Small-Particle Air Pollution May Raise Glaucoma Risk in Some Small-Particle Air Pollution May Raise Glaucoma Risk in Some

In people who already have a genetic vulnerability, small-particle air pollution known as black carbon may raise the risk of developing glaucoma, a new study suggests.Reuters Health Information
Source: Medscape Ophthalmology Headlines - Category: Opthalmology Tags: Ophthalmology News Source Type: news

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Condition:   Glaucoma Interventions:   Device: Citicoline eye drops (OMK1);   Other: Placebo Comparator: hypromellose based ocular lubricant Sponsors:   Istituto di Ricerca Neuroftalmologia S.r.l.;   University of Milan Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Inflammation underpins and contributes to the pathogenesis of many retinal degenerative diseases. The recruitment and activation of both resident microglia and recruited macrophages, as well as the production of cytokines, are key contributing factors for progressive cell death in these diseases. In particular, the interleukin 1 (IL-1) family consisting of both pro- and anti-inflammatory cytokines has been shown to be pivotal in the mediation of innate immunity and contribute directly to a number of retinal degenerations, including Age-Related Macular Degeneration (AMD), diabetic retinopathy, retinitis pigmentosa, glaucoma...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Condition:   IOP Decreased Intervention:   Procedure: MODIFIED TRABECULECTOMY Sponsor:   Assiut University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
To report the first case of a cerebral arteriovenous malformation (AVM) with ocular symptoms and review the characteristics of this case and the main point of confusion for the diagnosis of such a case.
Source: BMC Ophthalmology - Category: Opthalmology Authors: Tags: Case report Source Type: research
The effect of cataract surgery on IOP in patients with primary open-angle glaucoma (POAG) is a subject of debate. We investigated the effect of cataract surgery by phacoemulsification on intraocular pressure (...
Source: BMC Ophthalmology - Category: Opthalmology Authors: Tags: Research article Source Type: research
AbstractIntroductionThe CoQun® study is a multicenter, controlled trial aimed to evaluate the neuroprotective effects of Coqun®, an ophthalmic solution of Coenzyme q10 (CoQ10) and Vitamin E (VitE), in patients affected by primary open-angle glaucoma (POAG). Pre-clinical studies and small non-controlled clinical trials have previously shown a potential role of CoQ10 and VitE in glaucoma neuroprotection, both in vitro and in vivo.MethodsRandomized, parallel arm, multicenter, double-blind study. POAG patients with an IOP ranging from 17 to 21  mm Hg on monotherapy with a prostaglandin analogue (PGA) will be consi...
Source: Advances in Therapy - Category: Drugs & Pharmacology Source Type: research
Conclusions: Diode laser TSCPC using the slow coagulation technique is a safe and effective technique for lowering IOP in patients with refractory glaucoma in Chinese eyes. PMID: 31284800 [PubMed - as supplied by publisher]
Source: Seminars in Ophthalmology - Category: Opthalmology Tags: Semin Ophthalmol Source Type: research
ConclusionsThe surgical technique reported here can be an option to relieve dellen-associated ocular pain due to a bleb formed after tube shunt surgery.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
Publication date: Available online 10 July 2019Source: Journal of Genetics and GenomicsAuthor(s): Wenmin Sun, Xueshan Xiao, Shiqiang Li, Jiamin Ouyang, Xueqing Li, Xiaoyun Jia, Xing Liu, Qingjiong Zhang
Source: Journal of Genetics and Genomics - Category: Genetics & Stem Cells Source Type: research
Publication date: Available online 10 July 2019Source: Progress in Retinal and Eye ResearchAuthor(s): Stephanie B. Syc-Mazurek, Richard T. LibbyAbstractAxonal degeneration is an active, highly controlled process that contributes to beneficial processes, such as developmental pruning, but also to neurodegeneration. In glaucoma, ocular hypertension leads to vision loss by killing the output neurons of the retina, the retinal ganglion cells (RGC). Multiple processes have been proposed to contribute to and/or mediate axonal injury in glaucoma including: neuroinflammation, loss of neurotropic factors, dysregulation of the neuro...
Source: Progress in Retinal and Eye Research - Category: Opthalmology Source Type: research
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