Localized Ureteral Amyloidosis Mimicking Urothelial Carcinoma Localized Ureteral Amyloidosis Mimicking Urothelial Carcinoma

How was the unusual origin of this patient's left-sided flank pain determined?Applied Radiology
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Radiology Journal Article Source Type: news

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ConclusionThis study identified the most accurate and reliable machine learning methods, which could enhance the application of radiomics methods in the precision of diagnosis of NPC.
Source: Molecular Imaging and Biology - Category: Molecular Biology Source Type: research
In this study, we identified a naturally occurring pDC subset expressing high levels of OX40 (OX40+ pDC) enriched in the tumor microenvironment (TME) of head and neck squamous cell carcinoma. OX40+ pDCs were distinguished by a distinct immunostimulatory phenotype, cytolytic function, and ability to synergize with conventional DCs (cDCs) in generating potent tumor antigen–specific CD8+ T cell responses. Transcriptomically, we found that they selectively utilized EIF2 signaling and oxidative phosphorylation pathways. Moreover, depletion of pDCs in the murine OX40+ pDC–rich tumor model accelerated tumor growth. Co...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Authors: Piraccini E, Calli M, Taddei S, Byrne H, Rocchi M, Maitan S PMID: 32449341 [PubMed - as supplied by publisher]
Source: Minerva Anestesiologica - Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research
Authors: Abdelhamid BM, Khaled D, Mansour M, Hassan MM Abstract BACKGROUND: Pain control in the morbidly obese has presented as an anesthetic challenge. The aim of this study is to assess the analgesic efficacy of ultrasound guided bilateral erector spinae block compared to bilateral subcostal transversus abdominis plane block. METHODS: Prospective randomized, double-blinded controlled study was conducted at Kasr Alainy Hospital on 66 patients scheduled for laparoscopic sleeve gastrectomy. Patients were randomly allocated into three groups and received general anesthesia: bilateral erector spinae block at the l...
Source: Minerva Anestesiologica - Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research
Publication date: August 2020Source: Biomedicine &Pharmacotherapy, Volume 128Author(s): Hanif Khan, Wenting Jia, Zhuo Yu, Tahir Zaib, Jun Feng, Yanan Jiang, Haibin Song, Yunlong Bai, Baofeng Yang, Hai Feng
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
In the lumbar spinal cord dorsal horn, release of afferent nerve glutamate activates the neurons that relay information about injury pain. Here, we examined the effects of protein tyrosine kinase (PTK) inhibition on NMDA receptor NR1 subunit protein expression and subcellular localization in an acute experimental arthritis model. PTK inhibitors genistein and lavendustin A reduced cellular histological translocation of NMDA NR1 in the spinal cord occurring after the inflammatory insult and the nociceptive behavioral responses to heat. The PTK inhibitors were administered into lumbar spinal cord by microdialysis, and seconda...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Conclusion: Lateral window opening combined with digital navigation system is believed to be a promising technique for a more precise as well as safer sinus augmentation.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
AbstractBackgroundCombination therapy of interferon and ribavirin has traditionally been used to eradicate hepatitis C virus. The sustained virologic response achieved with interferon-related therapy is persistent, and late relapses after achieving sustained virologic response at 24  weeks using this therapy are reportedly rare (
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
ConclusionsThe tested BFB splint is highly effective in reducing SB at the subconscious level, i.e., without waking the patient, and in achieving improvements in global pain perception. The results suggest that the BFB splint also provides a better treatment option for bruxism-related pain than an AOS. However, further research is needed, and specifically studies with a larger patient population displaying higher levels of pain at baseline.Clinical relevanceBy reducing burst duration and therefore the pathological load on the masticatory apparatus, the BFB splint reduces TMD and bruxism-related symptoms and improves patien...
Source: Dental Technology Blog - Category: Dentistry Source Type: news
Publication date: Available online 25 May 2020Source: Progress in Neuro-Psychopharmacology and Biological PsychiatryAuthor(s): Ana M. Micov, Maja A. Tomić, Marija B. Todorović, Milja J. Vuković, Uroš B. Pecikoza, Nebojsa I. Jasnic, Jelena D. Djordjevic, Radica M. Stepanović-Petrović
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
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