Acquired resistance to an epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) in an uncommon G719S EGFR mutation

Discussion The newly established G719S-GR cell line may be useful for investigating the mechanism underlying the development of AR in the G719X mutation; the loss ofPTEN may be one such mechanism.
Source: Investigational New Drugs - Category: Drugs & Pharmacology Source Type: research