Model to Select On-Therapy vs Off-Therapy Tests for Patients With Refractory Esophageal or Extraesophageal Symptoms

It is not clear whether we should test for reflux in patients with refractory heartburn or extraesophageal reflux (EER) symptoms, such as cough, hoarseness, or asthma. Guidelines recommend testing patients by pH monitoring when they are on or off acid-suppressive therapies based on pretest probability of reflux, determined by expert consensus. However, it is not clear what constitutes a low or high pretest probability of reflux in these patients. We aimed to develop a model that clinicians can use at bedside to estimate pretest probability of abnormal reflux.

Source: Gastroenterology - August 28, 2018 Category: Gastroenterology Authors: Dhyanesh A. Patel, Rohit Sharda, Yash A. Choksi, James C. Slaughter, Tina Higginbotham, C. Gaelyn Garrett, David O. Francis, Karthik Ravi, Stephen Hasak, David Katzka, C. Prakash Gyawali, Michael F. Vaezi Tags: Clinical —Alimentary Tract Source Type: research