Acute kidney injury in HIV ‐infected patients: a critical review

Acute kidney injury (AKI) is characterized by a rapid decline of renal function associated with worse outcomes. The purpose of the authors is to perform a critical review of the incidence, risk factors, pathogenesis and outcome of AKI in HIV ‐infected patients. Human immunodeficiency virus (HIV)‐infected patients have an increased risk of developing AKI, to which contribute both HIV‐dependent and HIV‐independent factors as well as the nephrotoxicity of drugs used. The increased risk of AKI in HIV‐infected patients and its nega tive impact on prognosis highlights the need for identification of patients at risk, creation of prevention strategies and management.HIV ‐infected patients have an increased risk of developing AKI, to which both HIV‐dependent and HIV‐independent factors contribute, as well as the nephrotoxicity of drugs used.The increased risk of AKI in HIV ‐infected patients and its negative impact on prognosis highlight the need for identification of patients at risk, creation of prevention strategies and management.

Source: HIV Medicine - November 8, 2018 Category: Infectious Diseases Authors: J Gameiro, J Agapito Fonseca, S Jorge, JA Lopes Tags: Reviews in Antiretroviral Research Source Type: research