Vaccination Strategy Can Prevent a Deadly Childhood Infection
The sound of pertussis, or whooping cough, is terrifying. It is the sound of someone coughing violently, and then gasping for air; the gasp is the “whoop” sound. Whooping cough is a highly contagious, potentially fatal respiratory disease, and a big problem in Texas.
Reported cases of pertussis, also known as whooping cough, have been on the rise since the 1980s, according to the Centers for Disease Control and Prevention.?"Whooping cough is becoming more common, unfortunately, for a variety of reasons???maybe declining vaccination rates or waning immunity from our previous vaccines," says Dr. Tina Ardon, a family medicine specialist [...]
Condition: Pertussis Intervention: Biological: Boostrix®-IPV combination vaccine Sponsors: University of Oxford; National Institute for Public Health and the Environment (RIVM); University of Turku Recruiting
In this study, clonal spread and variation ofB.pertussis virulence factor in isolated strains from Iranian patients have been analyzed. A total of 100B.pertussis isolates were obtained from Pertussis Reference Laboratory of Pasteur Institute of Iran. Real-time PCR were performed to confirm theB.pertussis strains. The genomic patterns ofB.pertussis strains were analyzed by pulsed-field gel electrophoresis (PFGE). Predominant alleles of local strains wereptxP3,ptxA1,prn2,fim 2-1,fim3-2, andcya2. PFGE results showed 25 patterns clustered into 18 PFGE groups. A few similarities between the circulating isolates, vaccine, and st...
This study shows that adding RTX antigen to an appropriate dose of aP can enhance protection against B. pertussis challenge in mice.
Whooping cough (pertussis) infections are most severe in newborns, and may be fatal. In populations where adults are not immunized, administering pertussis vaccines to newborns may minimize the risk of life-threatening whooping cough infections in infants.
The National Vaccine Program Office (NVPO) and the Office of Disease Prevention and Health Promotion (ODPHP) have collaborated to develop the “Your Best Shot” vaccine video series. These videos highlight the importance of vaccines across the lifespan. Each video focuses on a particular disease such as whooping cough, shingles, and pneumococcal disease. Viewing these videos helps people understand why they need to get vaccinated. View the promotional toolkit with graphics, tweets, and newsletter content and promote the importance of immunizations during National Immunization Awareness Month.