Multiple-Dose Pharmacokinetics, Pharmacodynamics, and Safety of the Urotensin-II Receptor Antagonist Palosuran in Healthy Male Subjects

Conclusion: Palosuran after multiple-dosing is a well-tolerated drug in healthy subjects, but this finding warrants further investigation in patients.Pharmacology 2018;102:339 –346
Source: Pharmacology - Category: Drugs & Pharmacology Source Type: research