Tramadol: Distinguishing the Pathophysiology of Serotonin Syndrome and Seizures

We read with interest the narrative review on tramadol-induced risks of serotonin syndrome and seizures by Hassamal et al.1 We would like to comment on the statement that these two complications result from excessive serotonergic activity.
Source: The American Journal of Medicine - Category: General Medicine Authors: Tags: Letter Source Type: research