Advances in the application of comprehensive two-dimensional gas chromatography in metabolomics

Publication date: Available online 24 October 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Emily A. Higgins Keppler, Carrie L. Jenkins, Trenton J. Davis, Heather D. BeanAbstractDue to excellent separation capacity for complex mixtures of chemicals, comprehensive two-dimensional gas chromatography (GC × GC) is being utilized with increasing frequency for metabolomics analyses. This review describes recent advances in GC × GC method development for metabolomics, organismal sampling techniques compatible with GC × GC, metabolomic discoveries made using GC × GC, and recommendations and best practices for collecting and reporting GC × GC metabolomics data.

Source: TrAC Trends in Analytical Chemistry - October 25, 2018 Category: Chemistry Source Type: research