Cincinnati Children ’s, UC Health research 1-second cancer treatment
The Proton Therapy Center operated by Cincinnati Children ’s Hospital and UC Health is one of the founding members of the FlashForward Consortium, an international group researching the use of high doses of proton beams delivered at ultra-high speeds to treat cancer. The so-called flash therapy, which is delivered in one to three sessions that each last less than one second, represents a promising new direction in the treatment of cancer. The 13-member consortium intends to expand on preclinical…
ConclusionsVMAT is now widely available, and high-quality VMAT plans that incorporate cardiac substructures into the optimization process can provide overall improvements in dose to OARs and, in particular, substantial sparing of critical cardiac structures. IMPT provides some incremental dosimetric improvements beyond cardiac-optimized VMAT, the clinical significance of which remains uncertain.
ConclusionRITI can be induced in patients with NSCLC through upregulated IgG and/or IgM. RITI response was not associated with proton versus photon therapy or with clinical outcomes in this small cohort and should be examined in a larger cohort in future studies.
This study was performed to determine the clinical and patient-reported outcomes for patients with PC treated with HFPT.
CONCLUSIONS: IMPT following IBR spared underlying organs and had low rates of acute toxicity. Reconstruction complications are more common in irradiated breasts, and reconstructive outcomes appear comparable with photon literature. Hypofractionation was associated with higher reconstruction failure rates. Further investigation of optimal dose-fractionation after IBR is needed. PMID: 31185327 [PubMed - as supplied by publisher]
PMID: 31166085 [PubMed - as supplied by publisher]
An international group of 22 liver cancer experts from 18 institutions met in Miami, Florida to discuss the optimal utilization of proton beam therapy (PBT) for primary and metastatic liver cancer. There was consensus that PBT may be preferred for liver cancer patients expected to have a suboptimal therapeutic ratio from XRT, but that PBT should not be preferred for all patients. Various clinical scenarios demonstrating appropriateness of PBT versus XRT were reviewed.
It is critical that rigorous evaluation of technology in radiation oncology be undertaken during the early stages of implementation or when there is a marked cost differential. Prospective clinical data proving the clinical effectiveness of emerging technology may not be available to guide proper investment and development. In these scenarios, models can be used to simulate expected clinical outcomes and predict comparative effectiveness and cost-effectiveness.1 In this edition of the Red Journal, 2 studies use model-based approaches to compare photon intensity modulated radiation therapy (IMRT) to proton beam therapy (PBT...
A first-of-its-kind study compares the cure rates and side effects of proton therapy and X-ray radiation for people with various forms of cancer.
CONCLUSION: This study showed that a complementary dose with proton seems to be a good option for the treatment of locally advanced nasopharyngeal carcinoma, particularly for T4N0M0. PMID: 31138519 [PubMed - as supplied by publisher]
MedStar Georgetown University Hospital has taken the lead in the Washington, D.C.-area proton therapy arms race. Though, it’s a fleeting accolade. The hospital unveiled to guests and media Wednesday its new proton therapy center — a $40 million investment — marking the beginning of a new treatment available to eligible cancer patients. It’s one of about 30 proton centers across the country, billed a s the only one of its kind in the region. Although, the Maryland Proton Treatment Center…