Pitfalls in the diagnosis and management of Kawasaki disease: An update for the pediatric dermatologist

Pediatric Dermatology, EarlyView.
Source: Pediatric Dermatology - Category: Dermatology Authors: Source Type: research

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The prediction of resistance to intravenous immunoglobulins (IVIG) is currently still one of the main research areas in Kawasaki disease (KD). Several studies have reported on the use of N-terminal pro-brain n...
Source: Pediatric Rheumatology - Category: Rheumatology Authors: Tags: Research article Source Type: research
Publication date: Available online 12 September 2019Source: Genes &DiseasesAuthor(s): Kanika Arora, Sandesh Guleria, Ankur Kumar Jindal, Amit Rawat, Surjit SinghAbstractKawasaki disease (KD) is a medium vessel vasculitis with predilection to cause coronary artery abnormalities. KD is now the most common cause of acquired heart disease in developed countries. Thrombocytosis is consistently found in patients with KD, usually in 2nd to 3rd week of illness. Thrombocytopenia has occasionally been reported in the acute phase of KD. An increase or decrease in platelet number in patients with KD was initially considered to be ...
Source: Genes and Diseases - Category: Genetics & Stem Cells Source Type: research
We present four KD patients associated with immunodeficiencies: one with X-linked agammaglobulinemia, one with HIV infection, and two with leukemia; one of these patients also had Down syndrome. We did a literature search to find out all reported cases of immunodeficiency with KD in children. In immunodeficiency disorders, the inability of the immune system to eradicate the pathogens coupled to an exaggerated inflammatory response, especially in chronic granulomatous disease, may lead to the development of KD. The study of patients with immunodeficiencies complicated with KD may shed light into the etiopathogenesis of the disease.
Source: Rheumatology International - Category: Rheumatology Source Type: research
AbstractTo evaluate serum levels of IL6 in patients with Kawasaki disease and compare it with CRP, and to assess the role of these biomarkers in predicting coronary changes and resistance to the first-line therapy of this disease in a subset of Indian population. A single centre prospective observational study was conducted amongst all Kawasaki disease patients for a period of 18  months from January 2017 at Institute of Child Health, Kolkata. Serum IL6 and CRP were compared at diagnosis and after 48 h of administering IVIG in patients who developed coronary changes with those who did not and also among the respo...
Source: Rheumatology International - Category: Rheumatology Source Type: research
In the original publication of the article, the sentence “The integral value was computed for each channel, and isointegral maps were constructed during depolarization and repolarization.” was published incorrectly under the abstract section.
Source: Heart and Vessels - Category: Cardiology Source Type: research
This study aims to analyze clinical and laboratory features of KD among an Italian cohort of infants.
Source: BMC Pediatrics - Category: Pediatrics Authors: Tags: Research article Source Type: research
Condition:   Kawasaki Disease Interventions:   Drug: IVIG;   Drug: Aspirin;   Drug: Methylprednisolone Sponsor:   Children's Hospital of Fudan University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Kawasaki Disease Interventions:   Drug: IVIG;   Drug: Aspirin;   Drug: Prednisolone Sponsor:   Children's Hospital of Fudan University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Kawasaki Disease Interventions:   Drug: IVIG;   Drug: Aspirin;   Drug: Methylprednisolone Sponsor:   Children's Hospital of Fudan University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Kawasaki Disease Interventions:   Drug: IVIG;   Drug: Aspirin;   Drug: Prednisolone Sponsor:   Children's Hospital of Fudan University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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