Respiratory sinus arrhythmia mediates links between borderline personality disorder symptoms and both aggressive and violent behavior - Thomson ND, Beauchaine TP.

Although emotion dysregulation (ED) is a core symptom of borderline personality disorder (BPD), tests of associations between ED and aggression and violence-which are common to BPD-are sparse. The authors evaluated mediating effects of an autonomic vulnera...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Violence and Weapons Issues Source Type: news

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ConclusionOur findings suggest that there is a need of multidisciplinary discussion and genetic testing after unexpected cardiac death in the young. We have to be more flexible in our evaluation of diseases and to consider even uncommon diseases including rare recessive inherited disorders. Our findings also suggest that the autosomal recessive PGM1-CDG might be highly associated with life-threatening cardiomyopathy with arrhythmia or sudden cardiac death as the first symptom presenting from childhood and adolescence.
Source: Forensic Science International: Genetics - Category: Forensic Medicine Source Type: research
Publication date: Available online 17 June 2019Source: Journal of Theoretical BiologyAuthor(s): Joshua Veasy, Yi Ming Lai, Stephen Coombes, Rüdiger ThulAbstractCardiac alternans, in which the membrane potential and the intracellular calcium concentration exhibit alternating peak amplitudes at consecutive beats, constitute a precursor to fatal cardiac arrhythmia such as sudden cardiac death. A crucial question therefore concerns the onset of cardiac alternans. Typically, alternans are only reported when they are fully developed. Here, we present a modelling approach to explore recently discovered microscopic alternans,...
Source: Journal of Theoretical Biology - Category: Biology Source Type: research
Authors: Rahal D, Chiang JJ, Bower JE, Irwin MR, Venkatraman J, Fuligni AJ Abstract Subjective social status (SSS) reflects one's perception of one's standing within society. SSS has been linked with health outcomes, over and above socioeconomic status, and is thought to influence health in part by shaping stress responsivity. To test this, the present study examined the links between SSS and psychological, hypothalamic-pituitary-adrenal (HPA) axis, and cardiovascular responsivity in a sample of 87 ethnically diverse late adolescents (Mage = 18.39 years). Participants rated their family's SSS while either in...
Source: Stress - Category: Research Tags: Stress Source Type: research
In Reply Dr Lambert and colleagues concur with my Viewpoint that data generated from wearable devices need to be further interpreted by experienced clinicians to adjudicate accurate results and avoid inappropriate diagnoses. With continually improving technology and design, these devices are capable of providing patients and clinicians with important information regarding arrhythmias. However, understanding the limitations of these devices is essential to avoid overreliance and to judiciously incorporate them into clinical practice.
Source: JAMA - Category: General Medicine Source Type: research
The slow pathway region (SPR) is commonly targeted during ablation of atrio-ventricular nodal reentrant tachycardia. However, its role in idiopathic ventricular arrhythmias (IVAs) remains unknown.
Source: Heart Rhythm - Category: Cardiology Authors: Source Type: research
The remarkable advances in high-performance computing and the resulting increase of the computational power have the potential to leverage computational cardiology towards improving our understanding of the pathophysiological mechanisms of arrhythmias such as Atrial Fibrillation (AF). In AF, a complex interaction between various triggers and the atrial substrate is considered to be the leading cause of AF initiation and perpetuation. In electrocardiography (ECG), P-wave is supposed to reflect atrial depolarization. It has been found that even during sinus rhythm (SR), in AF patients multiple P-wave morphologies are present...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Atrial fibrillation (AF) has been recognised as the most prevalent sustained arrhythmia. Recently, a growing body of evidence has suggested that AF might be involved in the progression of cognitive impairment (CIM), potentially extending into types of dementia. Accordingly, the purpose of the present study was to summarise the findings of investigations examining association between AF and cognitive function as well as highlighting the possible causes of discrepancy between the findings and reviewing the probable mechanisms of CIM in patients affected with AF.
Source: Heart, Lung and Circulation - Category: Cardiology Authors: Tags: Review Source Type: research
This study aimed to examine which specific emotion processes influence self-inflicted injury: basal respiratory sinus arrhythmia, baseline negative emotional intensity, emotional reactivity, or emotion regulation deficits. METHOD: Self-i...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news
The present study aims to test the hypothesis of biological hyperarousal and hyperreactivity underpinning the dysfunctional emotional processes of borderline personality disorder (BPD). Self-reported (quality and intensity of emotions) and physiological (respiratory sinus arrhythmia [RSA] and heart rate) data were collected in 14 clinical subjects with BPD and in 14 control subjects (healthy controls [HCs]), during the administration of six video clips with different emotional contents. Our findings showed a constant hyperarousal state (lower RSA) in the clinical group, supporting the hypothesis of a biological vulnerabili...
Source: The Journal of Nervous and Mental Disease - Category: Psychiatry Tags: Original Articles Source Type: research
Journal of Personality Disorders, Ahead of Print.
Source: Journal of Personality Disorders - Category: Psychiatry Authors: Source Type: research
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