Primary Vitreoretinal Natural Killer/T-Cell Lymphoma with Breast Involvement: A Case Report and Review of Literature

A 50-year-old woman developed recurrent vitreous opacities in her left eye. The first diagnostic vitrectomy revealed no significant abnormality. OCT showed multiple high-density reflective nodules. The ratio of Interleukin 6 to 10 was over 1 in her aqueous humor, and Epstein-Barr virus was present. Conventional immunohistochemistry examination of vitrectomy specimens was diffusely positive for CD2, CD3, Ki67. Highly-metabolic nodules were found in her right breast on PET-CT scan. Immunohistochemistry of the breast biopsy was suggestive of NK/T cell lymphoma.
Source: Survey of Ophthalmology - Category: Opthalmology Authors: Tags: Clinical Pathologic Reviews Source Type: research