Hemangioblastoma of the Optic Nerve

Optic nerve hemangioblastoma (ONH) is a rare tumor that is usually unilateral and most commonl occurs in the context of von Hippel-Lindau (VHL) disease. Differential diagnosis is based on clinical history and imaging. Magnetic resonance imaging with gadolinium enhancement is the most useful imaging modality as it can reveal flow voids and an absence of dural attachment, differentiating ONH from other more commonly encountered optic nerve tumors. ONH are usually well-circumscribed vascular lesions composed of stromal cells and vascular endothelial cells.

Source: Survey of Ophthalmology - October 12, 2018 Category: Opthalmology Authors: Lindsay A. McGrath, Hardeep Singh Mudhar, Sachin M. Salvi Tags: Major review Source Type: research