TWiV 514: Staying below the ADAR

The TWiVumvirate reviews this years crop of Nobel Prizes, and how cells prevent leakage of mitochondrial double-stranded RNA into the cytoplasm, which would otherwise lead to the production of interferon. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”&gt;&lt;/span&gt;&amp;lt;span data-mce-type=”bookmark” style=”display: inline-block; width: […]

Source: virology blog - October 7, 2018 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology ADAR1 Alu checkpoint blockade CTLA-4 degradosome directed evolution dsRNA helicase IFN innate immunity MDA5 mitochiondria mutagenesis Nobel Prize PD-1 phage display RNA sensor type 1 interferonopat Source Type: blogs