Oxidative stress does not contribute to the release of proinflammatory cytokines through activating the Nod-like receptor protein 3 inflammasome in patients with obstructive sleep apnoea.

CONCLUSIONS: The current study suggests that oxidative stress leads to inflammation by mechanisms other than activation of the NLRP3 inflammasome in OSA patients. Furthermore, both sleep apnoea and BMI influenced the serum concentration of inflammatory mediators.
PMID: 30284175 [PubMed - as supplied by publisher]

Source: Sleep and Breathing - October 3, 2018 Category: Sleep Medicine Authors: Tang T, Huang Q, Liu J, Zhou X, Du J, Wu H, Li Z Tags: Sleep Breath Source Type: research