Tailored meta-analysis: an investigation of the correlation between the test positive rate and prevalence

Meta-analysis may produce estimates that are unrepresentative of a test ’s performance in practice. Tailored meta-analysis (TMA) circumvents this by deriving an applicable region for the practice and selecting the studies compatible with the region. It requires the test positive rate, r and prevalence, p being estimated for the setting but previous studies have assume d their independence. The aim is to investigate the effects a correlation between r and p has on estimating the applicable region and how this affects TMA.

Source: Journal of Clinical Epidemiology - September 29, 2018 Category: Epidemiology Authors: Brian H. Willis, Dyuti Coomar, Mohammed Baragilly Tags: Original Article Source Type: research