Native T1 Mapping as a Biomarker of Underlying Ventricular Myopathy and its Reversal in Patients with Atrial Fibrillation and Preserved Ejection Fraction Undergoing Catheter Ablation

Atrial fibrillation (AF) is a progressive disease that is not only a consequence of structural, hemodynamic and electrophysiological remodeling but also a perpetuator of the same processes. These factors often coexist in a complex arrhythmogenic substrate characterized by infiltration of diffuse fibrosis in the myocardium.1 There is now compelling evidence to suggest that the substrate is rarely restricted to the atria alone, but rather commonly present as extensive myocardial remodeling throughout the myocardium.
Source: Heart Rhythm - Category: Cardiology Authors: Source Type: research