Nuclear envelope assembly defects link mitotic errors to chromothripsis

Nuclear envelope assembly defects link mitotic errors to chromothripsisNuclear envelope assembly defects link mitotic errors to chromothripsis, Published online: 19 September 2018; doi:10.1038/s41586-018-0534-zThe mitotic spindle prevents normal nuclear envelope assembly on missegregated chromosomes, leading to spontaneous envelope disruption of micronuclei and subsequent genome instability.

Source: Nature AOP - September 19, 2018 Category: Research Authors: Shiwei Liu Mijung Kwon Mark Mannino Nachen Yang Fioranna Renda Alexey Khodjakov David Pellman Source Type: research