A third perspective on the effects of general health checks may provide a less biased estimate. Author response

Bruun Larsen et  al. have performed a CACE analysis, which compares mortality among actual participants of the intervention group with a hypothesized group of participants in the control group in the Inter99 study [1]. CACE analyses could be a valuable supplement to existing analyses, if we did not have the result s from an intention-to-treat (ITT) analysis, but we have these results making CACE analyses unnecessary. The authors suggest on the basis of their CACE analyses that there is a beneficial effect of the Inter99 study on total mortality among those who participated in the health check and lifestyle in tervention.

Source: Journal of Clinical Epidemiology - May 23, 2018 Category: Epidemiology Authors: Anne Mette Bender, Charlotta Pisinger, Torben J ørgensen Tags: Letter to the Editor Source Type: research