LB1616 EpiX ™ expansion technology enables in vitro tissue engineering of skin using autologous patient-derived cells for regenerative medicine applications

It remains a challenge to preserve stem and progenitor cells during expansion of epidermal keratinocytes ex vivo under serum-free and feeder-cell-free culture condition. This limitation greatly hinders the development of advanced autologous cell and gene therapeutics for inherited skin diseases such as epidermolysis bullosa and injuries such as severe burns. We have developed a serum-free and feeder-cell-free culture technology (EpiX ™) that allows rapid generation of more than one-trillion epidermal keratinocytes while retaining the stem and progenitor cell population.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Tissue Regeneration and Wound Healing Source Type: research