Mechanism of Chinese herbal formula QHF against breast cancer MCF-7 cells invasion and migration

ConclusionQHF can prevent the proliferation, migration, and invasion of MCF-7 cells by inhibiting the HGF/c-Met and its downstream PI3K/Akt and MAPK/ERK signaling pathways; Thereby down-regulating the expresssion of HGF, p-Met, p-ERK1, p-ERK2, p-Akt, MMP-2, MMP-9, and VEGF.
Source: Chinese Herbal Medicines - Category: Complementary Medicine Source Type: research