Testosterone and follicle stimulating hormone (FSH)-dependent glyoxalase 1 up-regulation sustains the viability of porcine Sertoli cells through the control of hydroimidazolone (MG-H1) – and argpyrimidine-mediated NF-κB pathway

As SCs play a central role in germ cesurvival, their death may results in marked germ cell loss and infertility (Eid et al., 2012; Oliveira et al., 2015). As SCs play a central role in germ cell survival, their death may result in marked germ cell loss and infertility (Eid et al., 2012; Oliveira et al., 2015). As SCs play a central role in germ cell survival, their death may result in marked germ cell loss and infertility (Eid et al., 2012; Oliveira et al., 2015). Sertoli cells (SCs) are the only somatic cells within the seminiferous tubules and are essential for regulating spermatogenesis.

Source: American Journal of Pathology - August 17, 2018 Category: Pathology Authors: Cinzia Antognelli, Francesca Mancuso, Roberta Frosini, Iva Arato, Mario Calvitti, Riccardo Calafiore, Vincenzo Nicola Talesa, Giovanni Luca Tags: Regular Article Source Type: research